Retrospective analysis of multidrug resistance organism isolated from refractory wound in patients with burns

doi:10.3877/cma.j.issn.1674-1358.2019.01.005

Abstract

Abstract:

Objective

To investigate the multidrug resistance organism (MDRO) isolated from refractory wound in burns surgery wards, and to provide reference for prevention and control of refractory wound MDRO infection.

Methods

Refractory wound bacteriological data of patients who were treated in Burns Surgery Wards in the 905th Hospital of PLA Navy from January 2011 to December 2017 were collected. The distribution and detection rate of MDRO, specific drug resistance organism were analyzed, retrospectively.

Results

There were 270 MDRO strains isolated from refractory wound, among which Gram-positive and Gram-negative MDRO accounted for 47.41% and 52.59%, respectively. The top five MDRO strains were Staphylococcus aureus (125 strains), Pseudomonas aeruginosa (56 strains), Escherichia coli (30 strains), Klebsiella pneumoniae (19 strains) and Acinetobacter baumannii (18 strains). The average detection rate of MDRO was 77.14%. The detection rate of the above top five MDRO were 88.65%, 65.12%, 90.91%, 100.00% and 90.00%, respectively. Among those MDRO, there were 118 strains of methicillin-resistance Staphylococcus aureus (MRSA), 42 strains of carbapenem-resistance Pseudomonas aeruginosa (CR-PA), 12 strains of carbapenem-resistance Acinetobacter baumannii (CR-AB) and 5 strains of carbapenem-resistance Klebsiella pneumoniae (CR-KP), respectively.

Conclusions

MDRO isolated from refractory wound in burns surgery wards are diverse and the detection rates are high. Measures need to be strengthened for prevention and treatment of refractory wound MDRO infection.

Key words: Refractory wound, Multidrug resistance organism, Clinical distribution, Burns surgery

Jun Ni, Xianrong Xu, Ruicai Chen. Retrospective analysis of multidrug resistance organism isolated from refractory wound in patients with burns[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2019, 13(01): 23-27.

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