To investigate the effect of bedside fibrous bronchscope suction and alveolar lavage in patients with stroke associated pneumonia (SAP).

Total of 60 patients with stroke associated pneumonia were randomly divided into control group and experimental group, each group with 30 cases. The patients in control group were given treatement of sputum sucking and antibiotic drugs. Sputum sucking was replaced with bedside fibrous bronchscope suction and alveolar lavage in experimental group. The blood gas, serum levels of inflammatory factors and clinical pulmonary infection score of two groups were compared, respectively.

The results of blood gas (pH: 7.41 ± 0.04 and 7.15 ± 0.11, t = 2.280, P = 0.035; PaCO₂: 6.70 ± 1.41 kPa and 11.42 ± 1.86 kPa, t = 6.290, P = 0.000; PaO₂: 10.33 ± 1.42 kPa and 5.77 ± 2.01 kPa, t = 5.320, P = 0.000), serum inflammatory factors (CRP: 95.86 ± 42.35 mg/L and 131.47 ± 33.53 mg/L; PCT: 3.27 ± 1.12 ng/ml and 7.57 ± 1.46 ng/ml; IL-6: 63.52 ± 13.68 ng/L and 94.47 ± 21.34 ng/L; TNF-α: 35.41 ± 8.42 ng/L and 54.62 ± 11.57 ng/L, P all < 0.01) and clinical pulmonary infection score (the third day: 4.0 ± 1.1 and 4.5 ± 1.3, t = 2.180, P = 0.045; the senventh day: 2.8 ± 1.0 and 3.4 ± 1.2, t = 2.690, P = 0.009) in experimental group were significantly superior to those in control group.

Bedside fibrous bronchoscope suction combined with alveolar lavage is a safe and effective method for treatment of SAP. It has high clinical value, and is worth application in clinic.