To investigate the prognostic risk factors of patients with cirrhosis and bacterial infection.

From January 2014 to February 2016, a total of 120 patients with liver cirrhosis and bacterial infection were collected and treated in Dongguan Qiaotou Hospital, Guangdong Province. The patients were followed up for two years and divided into death group (52 cases) and survival group (68 cases) according to their survival conditions. The white blood cell count, neutrophils, serum sodium and C-reactive protein levels, age, sex, gastrointestinal bleeding, Child-Pugh grade, pulmonary infection and urinary tract infection were compared between the two groups, respectively. Multivariate Logisitic regression analysis was used to analyze the correlation of the above factors and prognosis.

The leukocyte count, neutrophils and C-reactive protein levels of patients in death group were (11.70 ± 8.27) × 10⁹/L, (10.20 ± 7.50) × 10⁹/L and (61.38 ± 30.24) mg/L, respectively, significantly higher than those of survival group [(8.92 ± 6.38) × 10⁹/L, (7.48 ± 5.66) × 10⁹/L and (48.52 ± 20.11) mg/L] (t = 2.079, 2.264, 2.793; P = 0.040, 0.025, 0.006). In death group, there were 42 cases (80.77%) aged ≥ 50 , 25 cases (48.08%) with gastrointestinal hemorrhage, 41 cases (78.85%) with Child-Pugh grade C and 32 cases (61.54%) with pulmonary infection, respectively, all significantly higher than those of survival group [33 cases (48.53%), 16 cases (23.53%), 38 cases (55.88%) and 27 cases (39.71%), respectively (χ² = 13.068, 7.894, 6.908, 5.620; P = 0.000, 0.005, 0.009, 0.018). Multivariate Logisitic regression analysis showed that white blood cell count, neutrophils, C-reactive protein, age ≥ 50 years old, gastrointestinal bleeding, complicated with pulmonary infection, complicated with urinary tract infection were independent risk factors of death for patients with cirrhosis and bacterial infection (all P < 0.05).

There are more risk factors for death in patients with cirrhosis and bacterial infection. Clinically, comprehensive analysis should be carried out and targeted preventive measures should be worked out.