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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2017, Vol. 11 ›› Issue (06): 587-590. doi: 10.3877/cma.j.issn.1674-1358.2017.06.013

• Clinical Research Article • Previous Articles     Next Articles

Antimicrobial susceptibility analysis of 110 fungal isolates from patients with dermatophytes

Jiangqin Song1,(), Lirong Han1, Xiongbiao Liu2, Xiaohong Wang2   

  1. 1. Department of Clinical Laboratory, The First People’s Hospital of Tianmen, Tianmen 431700, China
    2. Dermatology, The First People’s Hospital of Tianmen, Tianmen 431700, China
  • Received:2016-12-09 Online:2017-12-15 Published:2021-09-08
  • Contact: Jiangqin Song

Abstract:

Objective

To investigate the clinical features of dermatophytes and the resistance of the isolates to several antifungal agents, and to guide the clinical treatment of dermatophytes.

Methods

During June 2015 to June 2016, direct fungi microscopy, culture and susceptibility testing from dermatophytes patients at a hospital dermatology clinic were taken.

Results

Among the 110 cases, 49 cases (44.5%) were with skin ringworm tinea, 30 cases (27.3%) with jock itch, 16 cases (14.5%) with tinea, 9 cases (8.2%) with tinea capitis and 6 cases (5.5%) with onychomycosis. The strains isolated from tinea patients were 28 strains (25.5%) of Trichophyton rubrum, 12 (10.1%) of Microsporum canis, 4 strains (3.6%) of Trichophyton mentagrophytes and 5 strains (4.5%) of Epidermophyton floccosum. The common isolated strains from tinea, brothers tinea, tinea capitis, onychomycosis were Trichophyton rubrum with 28 strains (25.5%), 13 strains (11.8%), 6 strains (5.4%), 6 strains (5.5%) and 5 strains (4.5%), respectively. The sensitivity of the isolated strains to clotrimazole was the highest (105 cases, 95.5%), followed by miconazole (93 cases, 84.5%), griseofulvin (51 cases, 46.4%) and fluconazole (104 cases, 94.5%).

Conclusions

Tinea corporis was the most common skin tinea disease (except the tinea), with the incidence rate of men higher than women, the most common clinical isolates was Trichophyton rubrum. 10% KOH tabletting microscopy and fungal culture were effective method for diagnosis of skin tinea disease, and was most sensitive to clonazole.

Key words: Dermatophytes, Fungal culture, Trichophyton rubrum

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