To investigate the clinical features of patients with liver failure complicated with aspergillus infection and the correlationship analysis.

Total of 300 patients with liver failure complicated with aspergillus infection were randomly selected from February 2013 to May 2015 in our hospital, while the clinical data of patients were analyzed, retrospectively.

The main cause of disease in patients with liver failure was viral hepatitis, HBV infection was the most common cause. Among the 185 patients, 20% patients were with the existence of few parts infection, the most common infection part was the abdominal cavity, followed by the lung. Some patients use a variety of antibiotics. Aspergillus fumigatus was the common Aspergillus, which accounted for more than 50%, followed by Aspergillusflavus and Aspergillus Niger. The correlation coefficient of bivariate analysis was 0.537 (P < 0.01), and the prognosis of basic disease was positively correlated with the effect of anti-Aspergillus.

Patients with liver failure should be attached importance to the treatment of basic diseases, rationally given antifungal drugs and maintain appropriate treatment.