To investigate the prevalence of cervical human papillomavirus (HPV) infection and genotype distribution in this region, and to provide reliable basis for cervical cancer prevention.

The genotypes of HPV among women of different ages cervical exfoliated cells specimens were detected by PCR and hybridization technique. According to the genotype, patients were divided into high-risk group, middle-risk group and low-risk group. The infection rate, genotype and age distribution of HPV in the female population were analyzed, respectively.

The positive rate was 47.18% (1 272/2 696). Among the positive 1 272 cases, the percentage of single HPV infection and multiple HPVs infection were 61.32% (780/1 272) and 38.68% (492/1 272). Positive cases was detected 2 053 cases, high-risk genotypes were found 1 307 times (63.66%) which was higher than 475 times in low risk (23.14%) and 271 (13.20%) times in middle-risk group. The positive rate of HPV infection in patients who were 20 or younger than 20 years old was 66.67%, meanwhile, it was 39.06% in patients older than 60 years old, with significant differences (χ² = 28.619, P < 0.001). As to constituent ratio of positive cases, patients of 21 to 30 years old was 29.17%, patients of 31 to 40 years old was 32.31% and patients of 41 to 50 years old was 25.86%, which were higher than other groups, with significant differences (χ² = 885.1, P < 0.001). Among the high-risk genotypes, HPV 16, 52, 58 were found more common than other genotypes. Among the low-risk genotypes, HPV 6, 11 were found more common than other genotypes, with significant difference (χ² = 1 678, P < 0.001).

Single infection and high-risk infection took the main part in the HPV infection in the region of department of gynaecology patients, subtype of the highest infection rates are high risk 16 genotypes. There existed a slight difference in infection rates of different age groups.