Artesunate combined with blood purification therapy for two cases of severe falciparum malaria

doi:10.3877/cma.j.issn.1674-1358.2016.06.022

Abstract

Abstract:

Objective

To investigate the characteristics of severe falciparum malaria and the effect of artesunate combined with blood purification for severe falciparum malaria.

Methods

The clinical data, treatment and prognosis of 2 cases with severe falciparum malaria were analyzed, retrospectively.

Results

Both cases with severe falciparum malaria cases were overseas input, and both had a clear life history of endemic falciparum malaria area. Both cases were middle-aged men, the main clinical symptom was fever. The conditions of both patients developed rapidly. They occurred consciousness soon, and accompanied by acute liver function, renal function failure and shock. Both cases with severe falciparum malaria were cured by artesunate combined with blood purification. Long-term follow-up indicated that neither of them recrudesced with malaria.

Conclusions

Early diagnosis of severe falciparum malaria, timely artesunate antimalarial treatment, early and continuous blood purification, and timely symptomatic treatment, may improve the prognosis for severe falciparum malaria.

Key words: Artesunate, Blood purification, Severe falciparum malaria, Acute renal failure

Xiaolan Xu, Jun Shao, Hua Lin, Ruiqiang Zheng. Artesunate combined with blood purification therapy for two cases of severe falciparum malaria[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2016, 10(06): 746-748.

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