To investigate the clinical effects of high sensitivity C-reactive protein (hs-CRP) combined with routine blood test in diagnosis of bacterial infectious diseases in children.

Total of 45 children with bacterial infectious diseases in our hospital from August 2014 to February 2015 were collected as the observation group, and 45 cases of healthy children as control group. The children were treated by hs-CRP test, blood test and joint detection of both, the detection index of the two groups and three detection method in the diagnosis of coincidence rate in the observation group were compared, respectivly.

After detection, the levels of hs-CRP, white blood cell count, neutrophil count in the observation group were (13.75±8.52) mg/L, (11.02±4.31) × 10⁹/L and (7.52±2.65) × 10⁹/L respectively, which were significantly higher than those of control group, with significant differences (t = 8.943, P = 0.000; t = 5.672, P = 0.006; t = 3.417, P = 0.011). In addition, the positive rate of hs-CRP combined with routine blood test was significantly higher than that of the separate detection of hs-CRP or routine blood test, with significant differences (χ²= 12.114, P = 0.000; χ²= 3.814, P = 0.025).

The pediatric infectious disease diagnosis by hs-CRP combined with routine blood test, will improved the diagnosis rate effectively, which should be promoted in the clinical application.