To improve the awareness of brucellosis in pregnancy among clinical medical staff.

The treatment process of a pregnant woman with brucellosis during pregnancy enrolled in Hohhot Second Hospital on December, 2019 was analyzed, while the relevant literatures were reviewed.

This pregnant women occurred only slight fatigue, migratory joint pain and low back pain, with rose bengal plate agglutination test (RBPT) (+) and serum agglutination test (SAT) 1︰100 (++++) at the 20th week during pregnancy. This case had threatened abortion at the 30th week and delivered by caesarean section. The patient developed fever on the second day after delivery, and was given intravenous drip of ceftriaxone sodium and levofloxacin, and oral doxycycline tablets and rifapentine capsules. After 7 days, the body temperature of the case returned to normal. After maintaining the above treatment for 20 days, oral doxycycline tablets and rifapentine capsules were applied for 90 days and then suspended. The case was followed up for 6 months, without recurrence of brucellosis. The newborn was examined for RBPT (+) and SAT 1︰100 (+++) on the second day after delivery. After treatment with rifampicin and compound sulfamethoxazole for 60 days, the course of treatment ended. RBPT (+) and SAT 1︰100 (++) were examined on the 30th day after birth. The child was followed up for 6 months, with no recurrence and normal growth, both RBPT and SAT showed (+).

Brucellosis during pregnancy could lead to serious adverse consequences such as abortion, premature delivery and neonatal congenital brucellosis, which should be paid more attention.