A case of acquired immune deficiency syndrome combined with neurosyphilis and cytomegalovirus encephalitis and related literature review

doi:10.3877/cma.j.issn.1674-1358.2021.05.010

Abstract

Abstract:

Objective

To enhance the awareness on acquired immune deficiency syndrome (AIDS) combined with neurosyphilis and cytomegalovirus encephalitis.

Method

The process of diagnosis and treatment of one AIDS patient combined with neurosyphilis and cytomegalovirus encephalitis were analyzed, and the related literature were reviewed.

Results

On June 14th, 2019, a 21-year-old male AIDS patient with CD4⁺ T as 65 cells/μl was admitted to Zhongnan Hospital of Wuhan University due to fever and dysarthria. The case was diagnosed as mixed infection of treponema pallidum and cytomegalovirus after complete examination. The magnetic resonance imaging (MRI) of brain showed multiple abnormal intracranial signals. The condition of the patient was relieved and multiple abnormal intracranial signals were absorbed and the prognosis was relatively well after anti-treponema pallidum, anti-cytomegalovirus and initiation of highly active antiretroviral therapy (HAART) at the right moment.

Conclusions

For patients with AIDS combined with neurosyphilis and cytomegalovirus encephalitis, timely diagnosis, combined treatment with anti-treponema pallidum and anti-cytomegalovirus and initiation of HAART at the right moment could improve the prognosis.

Key words: Acquired immune deficiency syndrome, Neurosyphilis, Cytomegalovirus encephalitis

Yingying Zhou, Liping Deng, Zhiyan Lu, Zhiyin Su, Yong Xiong. A case of acquired immune deficiency syndrome combined with neurosyphilis and cytomegalovirus encephalitis and related literature review[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2021, 15(05): 350-355.

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References 25

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