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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2018, Vol. 12 ›› Issue (03): 307-312. doi: 10.3877/cma.j.issn.1674-1358.2018.03.021

Special Issue:

• Case Report • Previous Articles    

A case of acquired immune deficiency syndrome complicated with disseminated penicilliosis marneffei and hemophagocytic syndrome and the literature review

Zhongtao Wang1, Yong Xiong1,(), Liping Deng1, Sufang Tian2, Fei Chen3   

  1. 1. Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
    2. Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
    3. Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
  • Received:2017-09-11 Online:2018-06-15 Published:2018-06-15
  • Contact: Yong Xiong
  • About author:
    Corresponding author: Xiong Yong, Email:

Abstract:

Objective

To enhance the awareness on acquired immune deficiency syndrome (AIDS) complicated with disseminated penicilliosis marneffei (PSM), hemophagocytic syndrome (HPS) and histocytic necrotizing lymphadenitis (HNL).

Methods

The process of diagnosis and treatment of one AIDS patients complicated with disseminated PSM, HPS and HNL (suspected) was analyzed. The relevant literatures were reviewed.

Results

One 43 years old man with AIDS complicated with disseminated PSM, HPS and HNL (suspected) was enrolled and treated by comprehensive anti-infection, anti-inflammatory (low dose dexamethasone), liver protection and symptomatic support. The patient recovered normal temperature and discharged in stable condition after treatment.

Conclusions

Early diagnosis and treatment of PSM, HPS and HNL are the keys to reduce the mortality and improve the prognosis for patients.

Key words: Acquired immune deficiency syndrome, Disseminated penicilliosis marneffei, Hemophagocytic syndrome, Histocytic necrotizing lymphadenitis

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