To investigate the clinical characteristics and causes of nasal bleeding in patients with HIV/AIDS, and to explore the appropriate treatment methods and preventive measures.

The clinical data of 72 HIV/AIDS patients with epistaxis from December 2010 to February 2017, who were consulted from other divisions in our hospital were collected. The disease feature, relevant factors, and therapeutic method were anaylzed.

The nasal mucosa was majorly with dry, ulcers, erosion or atrophy of 24 cases among the 72 cases , 14 patients had nasal mucosal edema, 22 patients had nasal sinusitis, nasal vestigitis and other related diseases. Hemorrhage was mainly caused by ulceration of mucous membrane, erosion and edema (37 cases), the remaining patients were with arterial bleeding (21 cases) and venous hemorrhage (14 cases). The frequency of bleeding was mainly multiple, with 47 cases of more than 3 times, and 17 cases for the first time, and 8 cases for 2-3 times. The bleeding site was principally bilateral (43 cases) and unilateral hemorrhage was 29 cases. The above indexes were tested by χ² test of multiple rates, with significant differences (P all < 0.05). Abnormal blood routine and coagulation function occurred in 65 patients among the 72 cases, and the immune function of 70 patients decreased. There were 52 cases with successful cure after active treatment, 18 cases relieved and 2 cases were invalid.

The characteristics of HIV/AIDS patients with epistaxis associated with underlying diseases, and the clinical efficacy by nasal packing and endoscopic minimally invasive treatment was well, which could be supplemented by local flushing adjustable nasal moisturizing care measures can prevent, treat appropriately, improve the quality of patients life, and relieve the pain.