To investigate the distribution and drug resistance of Urology, and to provide help to treat urinary tract infections.

Total of 73 strains of pathogens isolated from urine culture in patients with urinary tract infections who were underwent the minimally invasive surgery of Urology during May 2013 and December 2014 were analyzed, retrospectively.

There were 23 strains were isolated from urine culture in patients who were underwent the surgery of percutaneous nephrolithotomy lithotomy, while 20 strains were isolated from urine culture in patients who were underwent the surgery of transurethral prostatectomy and 30 strains were isolated from urine culture in patients who were underwent the surgery of other minimally invasive surgerys. Among the 73 strains of pathogens, 55 strains (75.34%) were Gram-negative bacteria, 8 strains (10.96%) were Gram-positive bacteria, and 10 strains (13.70%) were fungi. Escherichia coli, Serratia marcescens and Pseudomonas aeruginosa were the top three Gram-negative bacteria. Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus were the top three Gram-positive bacteria. The two fungi were Candida tropicalis and Candida albicans, respectively. Five strains of extended-spectrum β-lactamases (ESBLs) were isolated from Gram-negative bacteria and one strains of methicillin-resistant Staphylococcus aureus was isolated from Gram-positive bacteria. Different antimicrobial drugs pathogens showed different resistances.

The most common pathogens causing urinary tract infections after minimally invasive surgery of urology was Escherichia coli, and antibiotics should be used rationally with the help of drug sensitivity test.