To investigate the risk factors of nosocomial infection during the ultrasound interventional treatment, and to provide a clinical basis for the prevention and control of infection, in order to reduce the incidence of nosocomial infection.

Total of 148 patients with ultrasound interventional treatment in our hospital were selected from August 2012 to December 2014. The culture and separation of pathogenic bacteria were carried out by BACTEC 9000 System, and the drug susceptibility test was carried out by K-B AGAR method, and the results of the drug sensitization were determined according to the CLSI 2005 standard. Data analysis was analyzed by SPSS 17.0.

The nosocomial infection rate was 11.63% among the patients treated by ultrasonic interventional therapy. The age, invasive treatment, hospitalization time and application of antibiotics were all risk factors of nosocomial infection. There were 29 cases with nosocomial infection among the 148 patients, and 31 strains of pathogenic bacteria were detected. There were 17 strains (54.84%) of Gram negative bacteria and 14 strains (45.16%) of Gram positive bacteria. Gram positive bacteria were sensitive to teicoplanin and acetazolamide, while the Gram negative bacteria were sensitive to meropenem and imipenem.

Understanding the risk factors of hospital-acquired infection had some guiding significance for controlling the infection of ultrasonic intervention. When nosocomial infection occurs, it should be treated with relatively sensitive antimicrobial agents based on the experimental results of the drug.