Abstract:

Viral encephalitis (meningitis) is a common disease of central nervous system infection (CNSI), with a high mortality rate. The clinical manifestations of CNSI are nonspecific and the traditional virus detection methods such as virus isolation and serological diagnosis, were limited by technical conditions, so it is difficult to make early diagnosis. Along with the development of molecular biology detection technology and other CSF laboratory examination methods, such as cytology and cytokine detections, the etiological diagnosis of viral infections of central nervous system is becoming more and more important. This artical reviewed the research progress of epidemiology and laboratory diagnosis of the viral infection of central nervous system.

Key words: Central nervous system infections, Virus, Laboratory diagnosis, Molecular biology methods, Cerebrospinal fluid