To investigate the outcome of the pregnancy women complicated with varicella in third trimester.

The clinical data of 15 pregnancy women complicated with varicella in third trimester from January 2011 to November 2014 in Beijing Ditan Hospital, Capital Medical University were analyzed, retrospectively.

Among the 15 cases, 5 (33.3%) cases were 29-34 weeks pregnant, they were with no serious complications and were cured after antiviral treatment in 2 weeks. Three patients of full-term pregnancy were natural birth, 2 patients were cesarean delivery, maternal were well recovered. Apgar scoring and weights of newborns were in the normal range, and they were not infected during 30 days followed up. Ten (66.7%) cases were 37-40 weeks pregnant. Eight patients delivered during treatment. Among those patients, 4 cases were cesarean delivery, and the rest were natural childbirth. And 3 patients delivered within 7 days of infection, and 5 patients had more than 7 days of infection. One newborn was infected because his mother was infected in the fifth day before delivered, but the baby’s symptoms were not serious and was cured by antiviral treatment. The Apgar scoring and weight of the remaining seven newborns were in the normal range, they were not infected during 30 days followed up. Eight delivery women were cured after 7-10 days antiviral treatment in hospital, another 2 pregnant women were cured and delivered after discharged from hospital. It had no adverse effect on the pregnancy and infants. The newborns were not infected during 30 days followed up. Varicella infection rates of newborn were 0% and 10% respectively for delivery women between 29-34 weeks pregnant and 37-40 weeks pregnant, with significant differences (P = 0.048).

It is very important for the pregnancy women complicated with varicella in third trimester to give positive antiviral therapy and symptomatic treatment. Trying best to delay the delivery is able to decrease the incidence of neonatal chickenpox potentially.