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中华实验和临床感染病杂志(电子版) ›› 2019, Vol. 13 ›› Issue (03) : 181 -184. doi: 10.3877/cma.j.issn.1674-1358.2019.03.002

所属专题: 文献

综述

获得性免疫缺陷综合征患者脊柱亚临床骨折研究进展
马睿1, 张强1,()   
  1. 1. 100015 北京,首都医科大学附属北京地坛医院骨科
  • 收稿日期:2018-11-04 出版日期:2019-06-15
  • 通信作者: 张强
  • 基金资助:
    北京市教育委员会科技计划一般项目(No. KM201810025029)

Progress of subclinical fracture of patients with acquired immune deficiency syndrome

Rui Ma1, Qiang Zhang1,()   

  1. 1. Orthopedic Department, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
  • Received:2018-11-04 Published:2019-06-15
  • Corresponding author: Qiang Zhang
  • About author:
    Corresponding author: Zhang Qiang, Email:
引用本文:

马睿, 张强. 获得性免疫缺陷综合征患者脊柱亚临床骨折研究进展[J]. 中华实验和临床感染病杂志(电子版), 2019, 13(03): 181-184.

Rui Ma, Qiang Zhang. Progress of subclinical fracture of patients with acquired immune deficiency syndrome[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2019, 13(03): 181-184.

随着获得性免疫缺陷综合征(AIDS)抗病毒药物治疗的广泛应用,AIDS患者寿命已接近常人,越来越多的研究表明,AIDS患者应用高效联合抗反转录病毒治疗(HAART)后不仅出现骨质疏松脆性骨折,且椎体亚临床骨折发生率亦较健康人群显著增高,HAART此项并发症的危害逐渐受到临床医生的重视。本文就AIDS患者椎体亚临床骨折的定义、临床诊断、流行病学、发生机制以及防治措施等方面的研究进展做一综述。

With the wide application of anti-viral drugs for the treatment of acquired immune deficiency syndrome (AIDS), the life of patients with AIDS is nearly normal, and more and more studies showed that the application of high-efficiency combined anti-retroviral therapy (HAART) in patients with AIDS not only cause a brittle fracture of the osteoporosis, but also a significantly higher incidence of subclinical fracture of the vertebral body than that of the healthy people. The harm of the complication of HAART is gradually causing the attention of the clinician. This paper reviews the development of the definition, clinical diagnosis, epidemiology, mechanism and prevention and control measures of the subclinical fracture of the vertebral body in patients with AIDS.

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