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中华实验和临床感染病杂志(电子版) ›› 2017, Vol. 11 ›› Issue (03) : 218 -221. doi: 10.3877/cma.j.issn.1674-1358.2017.03.003

综述

中枢神经系统病毒性感染的实验室诊断研究进展
高世超1, 曹敬荣1, 王培昌1,()   
  1. 1. 100053 北京,首都医科大学宣武医院检验科
  • 收稿日期:2016-03-11 出版日期:2017-06-15
  • 通信作者: 王培昌
  • 基金资助:
    首都临床特色重点专项基金(No. Z141107002514012)

Advances on laboratory diagnosis of viral infections of central nervous system

Shichao Gao1, Jingrong Cao1, Peichang Wang1,()   

  1. 1. Department of Clinical Laboratory, Xuanwu Hospital of Capital Medical University, Beijing 100053, China
  • Received:2016-03-11 Published:2017-06-15
  • Corresponding author: Peichang Wang
引用本文:

高世超, 曹敬荣, 王培昌. 中枢神经系统病毒性感染的实验室诊断研究进展[J]. 中华实验和临床感染病杂志(电子版), 2017, 11(03): 218-221.

Shichao Gao, Jingrong Cao, Peichang Wang. Advances on laboratory diagnosis of viral infections of central nervous system[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2017, 11(03): 218-221.

病毒性脑炎(脑膜炎)是常见的中枢神经系统感染性疾病,人体感染后有较高的致死致残率。因临床表现的非特异性及传统病毒检测方法(如病毒分离培养及血清学诊断等)技术条件的局限性,临床早期病原体诊断较为困难。随着分子生物学检测技术及其他脑脊液实验室检查方法(如细胞学和炎性细胞因子检测)的不断发展,其在中枢神经系统病毒感染的病原诊断中越来越重要。本文就中枢神经系统病毒感染的流行病学及实验室诊断研究进展进行综述。

Viral encephalitis (meningitis) is a common disease of central nervous system infection (CNSI), with a high mortality rate. The clinical manifestations of CNSI are nonspecific and the traditional virus detection methods such as virus isolation and serological diagnosis, were limited by technical conditions, so it is difficult to make early diagnosis. Along with the development of molecular biology detection technology and other CSF laboratory examination methods, such as cytology and cytokine detections, the etiological diagnosis of viral infections of central nervous system is becoming more and more important. This artical reviewed the research progress of epidemiology and laboratory diagnosis of the viral infection of central nervous system.

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