Abstract:

Real world clinical studies refer to clinical studies conducted in real practice to evaluate effect of certain therapy on patients’ health. RWS data may be get from multiple sources which include hospital, community and home. Real world studies can be divided into observational studies and experimental studies. Real world studies always enrolled large sample size of real practice patients. In evidence based medicine system, evidence from real world studies are important supplement to evidence from randomized controlled studies. The concept of real world studies was literally reported in 1993 for the first time. Globally, real world studies develop rapidly in recent 10 years. Yet quality of real world studies in China still need to be improved. This practice algorithm on real world study were drafted to provide reference to related clinicians and researchers.

Key words: Real world study, Randomized controlled study, Evidence based medicine