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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (01): 34-38. doi: 10.3877/cma.j.issn.1674-1358.2025.01.006

• Reviews • Previous Articles     Next Articles

Research progress of vascular graft infection

Wangziyan Lu1, Yan Wang2, Yuanxing Wu2,()   

  1. 1. The Sixth Clinical Medical School, Capital Medical University, Beijng 100029, China
    2. Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijng 100029, China
  • Received:2024-11-08 Online:2025-02-15 Published:2025-04-28
  • Contact: Yuanxing Wu

Abstract:

Vascular graft infection (VGI) is a serious complication that can occur after vascular transplantation.Although the incidence of vascular graft infection is relatively low, the impact is extremely serious.VGI not only leads to organ dysfunction, but also may even cause amputation of a limb, and can be life-threatening in severe cases.In addition, treatment of VGI requires longer hospitalization and high medical costs, placing great flnancial pressure on patients.Therefore, early recognition and prompt treatment of vascular graft infection is crucial.The occurrence of VGI is associated with a variety of factors, including intraoperative infection control, the patient’s immune status and types of graft.The clinical presentation of this complication is usually complex and may manifest as either a localized inflammatory response or result in systemic infection.The diagnosis of VGI requires a comprehensive evaluation of imaging flndings, blood cultures, and histopathology.In order to accurately assess the severity of the infection and the extent of the lesion, the physician also needs to perform a comprehensive analysis based on the patient’s situation.Currently,treatments for vascular graft infections are constantly evolving, ranging from the choice of antibiotics to surgical debridement and reconstructive surgery and clinical experience has been accumulated.Therefore, the aim of this review is to summarize the characteristics and clinical manifestations of VGI at different surgical sites, as well as to summarize the classiflcation, diagnostic criteria, risk factors and therapeutic advances of VGI, so as to provide reference for clinicians in the treatment of VGI.

Key words: Vascular graft, Infection, Treatment

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