To provide reference for early diagnosis and early treatment of cerebral paragonimiasis.

The clinical data of 3 children with cerebral paragonimiasis from January 2011 to December 2022 were analyzed, retrospectively, with "two convulsions within 3 days", "dizziness, limb numbness for 2 days" and "headache, nausea and fever for 3 days" as the main complaints in Renmin Hospital, Hubei University of Medicine.

All children had a history of eating crabs in epidemic areas. Paragonimus antigen skin test (PAIT) were all positive. Eosinophils (EOS) of 3 children increased significantly. One child’s head MRI showed "intracranial hematoma with tunnel sign". There were no abnormality in MRI examination of the othoer 2 children’s heads. The clinical data of 3 children reached the standard of paragonimiasis diagnosis with the scale of paragonimiasis integral diagnosis. Praziquantel (25 mg/kg, taken three times a day for 2 days, with an interval of 7 days, entered the next course of treatment; totally 2-5 courses). After treatment, 3 children’s eurological symptoms were completely controlled, EOS returned to normal, and all achieved clinical cure.

Cerebral MRI examination of paragonimiasis can be normal, while EOS and paragonimiasis integral diagnostic scale are of impotpant value in the diagnosis and treatment of cerebral paragonimiasis.