To investigate the clinical characteristics of Chlamydia psittaci infection.

The diagnosis and treatment of a patient admitted to Anhua County People’s Hospital in April 2022 with severe community-acquired pneumonia caused by Chlamydia psittaci and pancreatic injury were analyzed, while the relevant literatures were reviewed.

This patient had a clear history of contact with poultry, and the main symptoms were cough, sputum, fever and fatigue at the onset of the disease; one week later after admission, the condition gradually worsened and multiple organ dysfunction occurred. In Intensive Care Unit, the patient was confirmed to be infected with Chlamydia psittaci by metagenomic next-generation sequencing of the bronchial alveolar lavage fluid. After 21 days of intravenous infusion of moxifloxacin (0.4 g/time once a day) and 35 days of oral administration of doxycycline (0.1 g/time twice a day), the condition improved. Although pancreatic enzymes increased (the peak value: Serum amylase 710 U, lipase 548.6 IU/L) during the period, the overall prognosis was good. Follow-up for 2 months and lung CT re-examination showed that the lesions were basically absorbed, and the organ functions of this case basically returned to normal.

Chlamydia psittaci infection progresses rapidly, and definite diagnosis is extremely important to control the disease. After effective drug treatment, the overall prognosis is good, but it is necessary to closely monitor pancreas and other organ functions, and manage well at pharmacovigilance during the treatment.