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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (04): 276-280. doi: 10.3877/cma.j.issn.1674-1358.2021.04.010

• Short Research Article • Previous Articles     Next Articles

Risk factors of lower respiratory tract infection for children with tracheobronchial foreign body

Peipei Zhou1, Yanan Wu1, Ying Wang1, Ran Wang2,()   

  1. 1. Department of Infectious Diseases, Xuzhou Children’s Hospital Affiliated to Xuzhou Medical University, Xuzhou 221006, China
    2. Nursing Department, Xuzhou Children’s Hospital Affiliated to Xuzhou Medical University, Xuzhou 221006, China
  • Received:2020-08-18 Online:2021-08-15 Published:2021-10-13
  • Contact: Ran Wang

Abstract:

Objective

To investigate the risk factors of lower respiratory tract infection of children with foreign bodies of trachea and bronchus.

Methods

Clinical data of 108 children with tracheobronchial foreign bodies admitted to Xuzhou Children’s Hospital affiliated to Xuzhou Medical University from May 2017 to March 2019 were analyzed, retrospectively. All children were divided into infection group (51 cases) and non-infection group (57 cases) according to with lower respiratory tract infection or not. The risk factors of lower respiratory tract infection in children with tracheobronchial foreign body were analyzed by chi-square test or Fisher exact probability method and Logistic multivariate regression analysis.

Results

Age (< 2 years old) (χ2 = 18.091, P < 0.001), type of foreign body (χ2 = 8.731, P < 0.001), shape of foreign body (χ2 = 12.350, P < 0.001), foreign body retention time (≥ 7 d) (χ2 = 7.347, P = 0.001) were all significantly different between the cases of infection group and non-infection group; but gender (χ2 = 0.578, P = 0.155), foreign body location (χ2 = 0.249, P = 0.642), incidences of three concave sign (χ2 = 0.636, P = 0.127) and emphysema (χ2= 0.076, P = 1.289) were without significant differences. Logistic multivariate regression analysis showed that age (< 2 years old) (OR = 4.456, 95%CI: 2.030-6.883, P < 0.001), plant foreign body (OR = 2.685, 95%CI: 1.576-3.451, P < 0.001), non-smooth foreign body (OR = 1.648, 95%CI: 1.436-3.662, P = 0.007) and foreign body residence time (≥ 7 days) (OR = 1.750, 95%CI: 1.328-3.553, P = 0.003) were all risk factors of lower respiratory tract infection. Compared with children of non-infection group, the cases of infection group had longer length of hospitalization [(3.9 ± 0.7) days] and antibiotic application time [ (7.1 ± 0.3) days], with significant differences (t = 28.923, P < 0.001; t = 163.79, P < 0.001).

Conclusions

Age < 2 years old, plant foreign bodies, non-smooth foreign bodies and residence time ≥ 7 days were all risk fators to lower respiratory tract infection for children with tracheobronchial foreign bodies. Monitoring these risk factors could help to assess the condition of children with tracheobronchial foreign bodies and improve the outcomes.

Key words: Tracheobronchial foreign body, Children, Lower respiratory tract infection, Risk factor

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