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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2018, Vol. 12 ›› Issue (06): 621-624. doi: 10.3877/cma.j.issn.1674-1358.2018.06.019

Special Issue:

• Case Report • Previous Articles    

Clinical characteristics of cerebral paragonimiasis misdiagnosed as tuberculous pleurisy and literature review

Xiaoqin Lu1, Feifei Lei2, Rugui Li2, Jinke Li2, Jian Li2, Jing Yang2, Huabing Tan2,()   

  1. 1. Department of Infections Disease, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China; Department of Paediatrics, Fangxian County Renmin Hospital, Fangxian 442100, China
    2. Department of Infections Disease, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China
  • Received:2018-04-22 Online:2018-12-15 Published:2018-12-15
  • Contact: Huabing Tan
  • About author:
    Corresponding author: Tan Huabing, Email:

Abstract:

Objective

To investigate the clinical characteristics and misdiagnosis of paragonimiasis with pleural effusion as the main clinical manifestation.

Methods

A case of paragonimiasis with pleural effusion as main clinical manifestation was misdiagnosed as tuberculous pleurisy. After 3 months of anti-tuberculosis treatment, it was diagnosed as "cerebral paragonimiasis" due to "sudden convulsion twice" ; and furtherly diagnosed as "mixed paragonimiasis" .

Results

Cerebral paragonimiasis complicated with pleural effusion was easily misdiagnosed as tuberculous pleurisy. According to the clinical manifestation, eosinophil count (EOS), and combination with immunological examination and other methods, the diagnosis was confirmed. After 5 successive courses of praziquantel treatment, clinical cure were obtained.

Conclusions

The main measures to reduce misdiagnosis and mistreatment and prevent the occurrence of important organ paragonimiasis are inquiring about the history of the disease carefully, examining the physical examination carefully, and analyzing the results of auxiliary examination scientifically. The treatment of paragonimiasis should follow the principle of individuation, and patients with long history of paragonimiasis, especially the cerebral paragonimiasis, may need multi-courses of treatment.

Key words: Cerebral paragonimiasis, Epilepsy, Eosinophilic granulocyte

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