To explore the difference of the prognostic evaluation value of patients with AKI caused by sepsis in three evaluation criteria of KDIGO, APACHE Ⅱ and SOFA.

Clinical data of 250 patients with septic in department of intensive care medicine in our hospital from January 2013 to January 2015 were collected. APACHE Ⅱand SOFA scores of all patients were evaluated according to the worst value of physiologic variables in the first 24 h after ICU admission and was classified by KDIGO criteria. Discrimination and calibration of these three models were assessed by ROC curve. Besides, their effects on prognostic were evaluated by multiple Logistic regression analysis.

Among the 250 admissions, 145 patients developed into AKI with the incidence of 58%. There were 105 sepsis patients with non-AKI, accounting for 42%, and the overall mortality was 29.8%. There were of 72 cases (49.7%) in phase I with the mortality rate as 24.3%; phase Ⅱof 44 patients (30.3%) with the mortality rate as 36.6%; phase Ⅲ of 29 cases (20.0%) with the mortality rate as 75.4%. APACHE Ⅱ, SOFA score of sepsis patients with AKI were significantly higher than patients with non-AKI (t = 3.206, P < 0.05). In sepsis patients with AKI, Logistic multivariate regression analysis showed that APACHE Ⅱ higher than 22 points (OR = 4.50), the KDIGO stageⅠ, Ⅱ, Ⅲ (OR = 2.42, 7.53 and 43.00) were all predictors to in-hospital deaths.

All the three criterias of APACHE Ⅱ, SOFA and KDIGO present good discrimination and calibration in predicting the outcome.