To analyze the vaginal microecology of different age-groups, and to provide the evidence for the etiological diagnosis and treatment of vagina infection.

Total of 4 714 patients admitted to our hospital from July 2013 to February 2014 were divided into 6 groups (10 years old for group interval). Vulvovaginal secretions were examined with Gram stain examination of vaginal discharge and assessed microecology by Nugent score, dominant bacteria to analyze the relationship of vaginal microecology and pathogeny.

The abnormal vaginal microecology rate was 17.86% (842/4 714), the disorder rate was 82.14% (3 872/4 714). Among the disorder, the bacterial vaginosis constituent ratio was 11.96% (564/4 714), the vulvovaginal candidiasis ratio was 13.96% (658/4 714), the BV intermediate was 4.54% (214/4 714), the triehomonas vaginitis constituent ratio was 0.25% (12/4 714), the aerobic vaginitis was 4.37% (206/4 714) and mixed vaginitis was 6.32% (298/4 714), other abnormal microflora was 12.99% including dominant bacteria changed or disappeared. The 21-30 years old group (36.57%), 31-40 years old group (29.87%) and 41-50 years old group (16.63%) were the main groups of vaginal microecology disorder, and 21-30 years old group and 31-40 years old group were the main age distribution of the mixed vaginitis, BV/BV intermediate and VVC. With the increase of age, the pH, Nugent score and the density of Laetobacillus changed significantly (χ² = 8.45, 28.53, 4.55; P = 0.02, 0.005, 0.04).

High incidence of vagina infection in women of childbearing age. The vagina pH, density of Laetobacillus were closely related to age and infection, so the vaginal microecology tests of different age groups should be paied attention to.