To analyze the risk factors of newborn with infectious diseases and to make the corresponding clinical countermeasures.

The clinical data of 92 cases with infectious diseases who hospitalized in our department from January 2013 to December 2014 were analyzed, retrospectively.

The top three infection sites of infectious disease were the respiratory system (43 cases), digestive system (20 cases) and skin and soft tissue (16 cases), the rates were 46.74%, 21.74% and 17.39%; neonatal infectious diseases ranked the top three were pneumonia (47 cases), diaper dermatitis (14 cases) and impetigo (9 cases), the rates were 51.09%, 15.22% and 9.78%, respectively. The top three pathogens of neonatal infectious disease were Klebsiella pneumoniae (28 strains, 30.43%), Escherichia coli (18 strains, 19.57%) and Pseudomonas aeruginosa (16 strains, 17.39%).

Neonatal infection diseases were caused by a variety of factors, the awareness of infection control perinatal complications and hospital infection should be enhanced, the disinfection and isolation system should be implemented strictly and the aseptic operation process should be implemented strictly, which could reduce the rate of infectious diseases of newborn.