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Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition) ›› 2016, Vol. 10 ›› Issue (01): 69-72. doi: 10.3877/cma.j.issn.1674-1358.2016.01.016

• Clinical Research Article • Previous Articles     Next Articles

Diagnostic value of combined detection for levels of procalciton, C-reaction protein and count of white blood cell in diagnosis for respiratory tract infection

Xianwei Zeng1,()   

  1. 1. Clinical Laboratory, Songgang People’s Hospital, Baoan District, Shenzhen 518105, China
  • Received:2015-02-20 Online:2016-02-15 Published:2021-09-08
  • Contact: Xianwei Zeng

Abstract:

Objective

To investigate the clinical significance of combined detection for the levels of plasma procalciton (PCT), C-reaction protein (CRP) and counts of white blood cell (WBC) in diagnosis for respiratory tract infection.

Methods

Total of 104 patients with respiratory tract infections in our hospital from July 2013 to April 2014 were selected and divided into two groups according to with or without bacterial infection, while 40 healthy adults were selected as control group. The differences of levels of PCT, CRP and counts of WBC were compared between the two groups, respectively. The clinical efficiency of each index of combined detection for diagnosis of respiratory tract bacterial infections was calculated.

Results

The levles of PCT, CRP and counts of WBC in patients with bacterial infection were increased significantly than patients with non-bacterial infection (t = 9.316, 8.389, 8.495; P all = 0.000). The sensitivity of combined detection was compared with PCT, CRP and WBC detection, with significantly differences (χ2 = 30.687, 21.682, 22.753; P all = 0.000). Compared specificity of combined detection was compared with CRP and WBC detection, the differences were significant (χ2 = 11.665, 11.665; P all = 0.000).

Conclusions

The combined detection of levels of PCT, CRP and counts of WBC could effectively improve the clinical diagnosis rate for respiratory tract infection, and it was conducive to the judgment of bacterial infection and could provide related evidence for clinical rational drug application.

Key words: Procalcitonin, C-reaction protein, White blood cell, Respiratory tract infection, Bacterial infection

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