Risk factors of severe brain injury complicated with pulmonary infection

doi:10.3877/cma.j.issn.1674-1358.2016.01.012

Abstract

Abstract:

Objective

To investigate the risk factors of severe brain injury complicated with pulmonary infection, and to improve the level of clinical treatment by taking corresponding measures.

Methods

The data of 90 cases with severe traumatic brain injury collected from January 2011 to January 2014 were analyzed, retrospectively, among which, the risk factors of 29 cases with pulmonary infection were analyzed.

Results

Elderly (> 60 years), the ventilator applications, shock, tracheotomy, underlying disease, lung disease original, hypoalbuminemia, use of antibiotics and hormones and GCS score were factors of severe brain injury patients with lung infection (P all < 0.05). Sex and surgery were not correlated with lung infection (P > 0.05). Age (OR = 6.852), GCS score (OR = 7.483), underlying diseases (OR = 8.852), tracheotomy (OR = 5.597), antimicrobial agents (OR = 8.849) and the application of hormones (OR = 8.674) and shock (OR = 5.832) were risk factors of patients with severe brain injury complicated with lung infection (P all < 0.05).

Conclusions

Fully prepared and ready to actively prevent hospital-related treatment could reduce the rate of severe brain injury with pulmonary infection.

Key words: Severe brain injury, Lung infection, Risk factors, Treatment measures

Yan Liu, Yufei Gao, Qingyuan Li. Risk factors of severe brain injury complicated with pulmonary infection[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2016, 10(01): 54-56.

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Figures/Tables 2

References 14

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相关因素		例数	肺部感染者	χ²值	P值
高龄（> 60岁）		21	13（61.90）	7.893	< 0.05
使用呼吸机		70	28（40.00）	5.892	< 0.05
休克		32	19（59.38）	6.262	< 0.05
气管切开		49	21（42.86）	5.062	< 0.05
有基础疾病		39	20（51.28）	5.582	< 0.05
有手术史		23	7（30.43）	0.742	> 0.05
肺部原有疾病		19	11（57.89）	6.372	< 0.05
低蛋白血症		27	20（74.07）	5.852	< 0.05
使用激素		33	23（69.70）	6.042	< 0.05
使用抗菌药物		31	22（79.97）	5.762	< 0.05
性别
	男	62	20（32.26）	0.436	> 0.05
	女	28	9（32.14）	0.436	> 0.05
GCS评分（分）
	≤ 4	19	19（100.00）	7.256	< 0.05
	> 4	71	10（14.08）	7.256	< 0.05

相关因素		例数	肺部感染者	χ²值	P值
高龄（> 60岁）		21	13（61.90）	7.893	< 0.05
使用呼吸机		70	28（40.00）	5.892	< 0.05
休克		32	19（59.38）	6.262	< 0.05
气管切开		49	21（42.86）	5.062	< 0.05
有基础疾病		39	20（51.28）	5.582	< 0.05
有手术史		23	7（30.43）	0.742	> 0.05
肺部原有疾病		19	11（57.89）	6.372	< 0.05
低蛋白血症		27	20（74.07）	5.852	< 0.05
使用激素		33	23（69.70）	6.042	< 0.05
使用抗菌药物		31	22（79.97）	5.762	< 0.05
性别
	男	62	20（32.26）	0.436	> 0.05
	女	28	9（32.14）	0.436	> 0.05
GCS评分（分）
	≤ 4	19	19（100.00）	7.256	< 0.05
	> 4	71	10（14.08）	7.256	< 0.05

变量	β值	S.E.值	Wald值	P值	OR值	95%CI
年龄	2.023	0.883	5.387	0.025	6.852	1.356～13.384
GCS评分	1.647	0.837	5.636	0.001	7.483	1.387～27.363
基础疾病	1.946	0.845	5.595	0.021	8.852	1.752～26.484
气管切开	1.484	0.473	5.462	0.027	5.597	1.395～21.592
抗菌药物应用	1.495	0.385	5.480	0.021	8.849	1.749～25.495
激素应用	1.401	0.337	5.038	0.022	8.674	1.668～19.671
休克	1.358	0.349	5.429	0.011	5.832	1.474～21.344

变量	β值	S.E.值	Wald值	P值	OR值	95%CI
年龄	2.023	0.883	5.387	0.025	6.852	1.356～13.384
GCS评分	1.647	0.837	5.636	0.001	7.483	1.387～27.363
基础疾病	1.946	0.845	5.595	0.021	8.852	1.752～26.484
气管切开	1.484	0.473	5.462	0.027	5.597	1.395～21.592
抗菌药物应用	1.495	0.385	5.480	0.021	8.849	1.749～25.495
激素应用	1.401	0.337	5.038	0.022	8.674	1.668～19.671
休克	1.358	0.349	5.429	0.011	5.832	1.474～21.344

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