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中华实验和临床感染病杂志(电子版) ›› 2019, Vol. 13 ›› Issue (05) : 432 -435. doi: 10.3877/cma.j.issn.1674-1358.2019.05.015

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短篇论著

获得性免疫缺陷综合征合并白内障患者经系统高效抗反转录病毒治疗后围手术期感染控制疗效
许雪静1,(), 柳月红1, 刘彬彬1, 董愉1, 马爱民1, 陈宁1   
  1. 1. 100015 北京,首都医科大学附属北京地坛医院眼科
  • 收稿日期:2019-01-29 出版日期:2019-10-15
  • 通信作者: 许雪静
  • 基金资助:
    北京市属医院科研培育计划项目(No. PX2018061)

Effect of surgical infection control during perioperative period in patients with acquired immunodeficiency syndrome complicated with cataract after systemic highly effective antiretroviral therapy

Xuejing Xu1,(), YueHong Liu1, Binbin Liu1, Yu Dong1, Aimin Ma1, Ning Chen1   

  1. 1. Department of Ophthalmology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
  • Received:2019-01-29 Published:2019-10-15
  • Corresponding author: Xuejing Xu
  • About author:
    Corresponding author: Xu Xuejing, Email:
引用本文:

许雪静, 柳月红, 刘彬彬, 董愉, 马爱民, 陈宁. 获得性免疫缺陷综合征合并白内障患者经系统高效抗反转录病毒治疗后围手术期感染控制疗效[J/OL]. 中华实验和临床感染病杂志(电子版), 2019, 13(05): 432-435.

Xuejing Xu, YueHong Liu, Binbin Liu, Yu Dong, Aimin Ma, Ning Chen. Effect of surgical infection control during perioperative period in patients with acquired immunodeficiency syndrome complicated with cataract after systemic highly effective antiretroviral therapy[J/OL]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2019, 13(05): 432-435.

目的

探讨获得性免疫缺陷综合征(AIDS)合并白内障患者经系统高效抗反转录病毒治疗(HAART)后围手术期感染控制的疗效。

方法

回顾性分析首都医科大学附属北京地坛医院收治的10例AIDS合并白内障患者的术前基本资料及手术前后采取的感染防控方法,探讨其危险因素及防范措施。

结果

对10例AIDS合并白内障患者行HAART后,CD4+ T淋巴细胞计数上升至196~745个/μl,病情稳定,无并发症发生;其中8例患者给予白内障超声乳化术加人工晶体植入术。1例患者合并黄斑前膜,另外1例患者合并视网膜脱离,二者均给予玻璃体切割术+白内障超声乳化术+人工晶体植入术。10例AIDS合并白内障患者术后均未发生感染。

结论

AIDS合并白内障患者手术前给予系统高效抗逆转录病毒治疗(HAART),并严格执行术前消毒,术中无菌操作、术后观察及换药,可有效防止AIDS合并白内障患者术后感染的发生。

Objective

To investigate the effect of surgical infection control during perioperative period after systemic highly effective antiretroviral therapy (HAART) in patients with acquired immunodeficiency syndrome (AIDS) complicated with cataract.

Methods

The basic data of 10 patients with AIDS complicated with cataract before and after operation collected from Beijing Ditan Hospital, Capital Medical University were analyzed, retrospectively.

Results

After systemic highly effective antiretroviral therapy (HAART) for 10 cases with AIDS and cataract, the CD4+ T lymphocyte count increased to 196-745 cells/μl, witout complications. Eight patients received cataract phacoemulsification combined with intraocular lens implantation. One patient was complicated with macular membrane, and the other one was complicated with retinal detachment. Both the two cases were treated with vitrectomy combined with phacoemulsification and intraocular lens implantation. No infection occurred in all 10 patients with AIDS complicated with cataract.

Conclusions

HAART for AIDS patients with cataract before surgery, strict preoperative disinfection, intraoperative aseptic operation, postoperative observation and dressing change could effectively prevent the occurrence of postoperative infection in AIDS patients complicated with cataract.

表1 10例患者白内障术前基线资料及术后视力
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