总结获得性免疫缺陷综合征（AIDS）相关型卡波西肉瘤口腔病损的临床及治疗转归。

选取首都医科大学附属北京地坛医院感染科2014年3月至2015年12月收治的7例AIDS合并卡波西肉瘤的患者资料，对其临床特征、治疗及转归进行回顾性分析。

7例患者均为男性、汉族，平均年龄为（37 ± 14）岁，CD4⁺ T细胞计数范围为10～111个/μl。7例患者均有口腔病损，其中3例仅有口腔病损，4例同时伴皮肤病损，2例合并肺部受累。口腔损害部位仅1处患者3例，多处损害者4例，累及腭部者7例，累及牙龈者2例，累及舌者1例，累及唇者1例。7例患者中3例病情好转，其中2例单用高效抗逆转录病毒（HAART）治疗，1例患者应用HAART联合全身化疗，1例患者放弃化疗，自行出院。3例患者因卡波西肉瘤（KS）播散至肺部或合并有多发的机会性感染死亡。

AIDS相关型卡波西肉瘤临床多见于中青年男性，口腔病损可为首发症状，常伴皮肤损害或累及内脏，治疗方案根据病损范围选择高效抗逆转入病毒治疗或高效抗逆转入病毒治疗联合系统化疗为主。

To investigate the clinical characteristics and prognosis of patients with acquired immune deficiency syndrome (AIDS) related oral Kaposi’s sarcoma (KS).

The clinical characteristics, therapeutic responses and prognosis of 7 cases with AIDS-related oral Kaposi’s sarcoma admitted in Beijing Ditan Hospital, Capital Medical University from March 2014 to December 2015 were analyzed, retrospectively.

Total of the 7 cases were male and Han nationality, with the median age was (37 ± 14) years old, counts of CD4⁺ T cell were 10-111 cells/μl. All of 7 patients had oral lesions, among whom 3 cases with only manifested oral lesions, 4 cases with skin lesions, and another 2 cases with pulmonary lesions. Three cases had only one oral lesion, 4 cases had more oral lesions, including palate (7 cases), gingival (2 cases), tongue (1 case) and lip (1 case). There were 3 patients got better prognosis after receiving treatment, among whom, 2 patients received highly active antiretroviral therapy (HAART), 1 patient received HAART combined with systemic chemotherapy. Another 4 patients got worse prognosis, among whom 1 patient was gave up chemotherapy due to unaffordable further treatment, another 3 patients died due to KS metastasis or multiple opportunistic infections.

AIDS-related Kaposi’s sarcoma occurs usually among young man, oral lesions could be the first symptoms, often with skin lesions or involvement of internal organs, the treatment options according to the size of the damage to choose HAART or HAART combined chemotherapy.