伴放线放线杆菌性败血症一例

doi:10.3877/cma.j.issn.1674-1358.2017.01.021

中华实验和临床感染病杂志(电子版) ›› 2017, Vol. 11 ›› Issue (01) : 92 -94. doi: 10.3877/cma.j.issn.1674-1358.2017.01.021

病例报告

伴放线放线杆菌性败血症一例

金柯¹, 刘根焰², 李军¹, 翁亚丽¹^,^†(

)

^1. 210029　南京市，南京医科大学第一附属医院感染病科
^2. 210029　南京市，南京医科大学第一附属医院检验科

收稿日期:2015-09-14 出版日期:2017-02-15
通信作者: 翁亚丽
基金资助:
国家重大科技专项(No. 2013ZXl0002005-002-005；2013ZXl0004905); 江苏省医学创新团队与领军人才项目(No. LJ201121)

Report of one case with Aggregatibacter actinomycetemcomitans septicemia

Ke Jin¹, Genyan Liu², Jun Li¹, Yali Weng¹^,^†()

^1. Department of Infectious Diseases, the First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China
^2. Department of Laboratory Medicine, the First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China

Received:2015-09-14 Published:2017-02-15
Corresponding author: Yali Weng

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目的

探讨伴放线放线杆菌性败血症的临床特征及抗菌药物的选用。

方法

对本院收治的1例伴放线放线杆菌性败血症患者的临床资料、诊治经过及预后进行回顾性分析。

结果

本例伴放线放线杆菌性败血症患者为56岁男性，长期于地下停车场工作且以夜间为主，主要临床表现为低热、消瘦。血培养至第8天见细菌生长，第19天时鉴定为伴放线放线杆菌感染。给予莫西沙星抗感染治疗后，患者体温恢复并持续正常，复查炎性标志物等基本正常，复查血培养未见细菌生长。

结论

对于长程发热患者需尽早进行血培养，且当怀疑为苛养菌所致血流感染时血培养观察时间应延长；抗伴放线放线杆菌治疗可选择喹诺酮类药物。

关键词: 伴放线放线杆菌, 败血症

Objective

To investigate the clinical features and antibacterials selection of Aggregatibacter actinomycetemcomitans septicemia.

Methods

The clinical manifestations, treatment and prognosis of one patient with Aggregatibacter actinomycetemcomitans septicemia in our hospital in 2015 was analyzed, retrospectively.

Results

The case was a 56 years old man who worked at underground parking garage nightly. The main clinical manifestations were low-grade fever and weight loss. Bacterial growth appeared in blood culture at the eighth day after sampling, and identified as Aggregatibacter actinomycetemcomitans at the nineteenth day. After the treatment with moxifloxacin, the patient recovered, while the inflammatory markers returned to be nearly normal and no bacterium grew in the reexamination of blood culture.

Conclusions

Blood culture should be done as soon as possible to the patients with prolonged fever and the observation period for blood culture should be extended when a fastidious bacterium bloodstream infection is suspected. Moxifloxacin is appropriate for the treatment of Aggregatibacter actinomycetemcomitans infection.

Key words: Aggregatibacter actinomycetemcomitans, Septicemia

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Report of one case with Aggregatibacter actinomycetemcomitans septicemia

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Report of one case with Aggregatibacter actinomycetemcomitans septicemia