切换至 "中华医学电子期刊资源库"

中华实验和临床感染病杂志(电子版) ›› 2021, Vol. 15 ›› Issue (06) : 374 -378. doi: 10.3877/cma.j.issn.1674-1358.2021.06.003

综述

新型冠状病毒感染儿童皮肤损害
孟一星1, 黄辉1, 邓莉1,()   
  1. 1. 100020 北京,首都儿科研究所附属儿童医院感染科
  • 收稿日期:2021-04-27 出版日期:2021-12-15
  • 通信作者: 邓莉
  • 基金资助:
    北京市医院管理中心儿科学科协同发展中心专项(No. XTCX201822)

Cutaneous manifestations associated with severe acute respiratory syndrome coronavirus 2 among pediatrics

Yixing Meng1, Hui Huang1, Li Deng1,()   

  1. 1. Department of Infectious Diseases, Capital Institute of Pediatrics Affiliated Children Hospital, Beijing 100020, China
  • Received:2021-04-27 Published:2021-12-15
  • Corresponding author: Li Deng
引用本文:

孟一星, 黄辉, 邓莉. 新型冠状病毒感染儿童皮肤损害[J/OL]. 中华实验和临床感染病杂志(电子版), 2021, 15(06): 374-378.

Yixing Meng, Hui Huang, Li Deng. Cutaneous manifestations associated with severe acute respiratory syndrome coronavirus 2 among pediatrics[J/OL]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2021, 15(06): 374-378.

新型冠状病毒(SARS-CoV-2)感染相关的皮肤损害已陆续被报道。本文总结儿童新型冠状病毒感染者皮肤损害的类型及特点,并分析其病理机制、鉴别诊断、治疗及预后,以丰富临床医师对新型冠状病毒感染相关疾病的认知,做到早期鉴别和治疗。

Cutaneous manifestations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported continuously. In this review, the types and characteristics of different skin lesions of COVID-19 children were summarized, and its pathological mechanism, differential diagnosis, treatment and prognosis were analyzed, so as to enrich the clinicians’ cognition of SARS-CoV-2 associated cutaneous manifestation, inorder to achieve early identification and treatment.

[1]
Pousa PA, Mendonca TSC, Oliveira EA, et al. Extrapulmonary manifestations of COVID-19 in children: a comprehensive review and pathophysiological considerations[J]. J Pediatr (Rio J),2021,97(2):116-139.
[2]
Lu S, Lin J, Zhang Z, et al. Alert for non-respiratory symptoms of coronavirus disease 2019 patients in epidemic period: A case report of familial cluster with three asymptomatic COVID-19 patients[J]. J Med Virol,2021,93(1):518-521.
[3]
Recalcati S. Cutaneous manifestations in COVID-19: a first perspective[J]. J Eur Acad Dermatol Venereol,2020,34(5):e212-e213.
[4]
Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China[J]. N Engl J Med,2020,382(18):1708-1720.
[5]
Hoang A, Chorath K, Moreira A, et al. COVID-19 in 7 780 pediatric patients: A systematic review[J]. E Clinical Medicine,2020,24:100433.
[6]
Chen Y, Peng H, Wang L, et al. Infants born to mothers with a new coronavirus (COVID-19)[J]. Front Pediatr,2020,8:104.
[7]
Wu P, Liang L, Chen C, et al. A child confirmed COVID-19 with only symptoms of conjunctivitis and eyelid dermatitis[J]. Graefes Arch Clin Exp Ophthalmol,2020,258(7):1565-1566.
[8]
Khalili M, Iranmanesh B, Mohammadi S, et al. Cutaneous and histopathological features of coronavirus disease 2019 in pediatrics: A review article[J]. Dermatol Ther,2021,34(1):e14554.
[9]
Andina D, Noguera-Morel L, Bascuas-Arribas M, et al. Chilblains in children in the setting of COVID-19 pandemic[J]. Pediatr Dermatol,2020,37(3):406-411.
[10]
Garcia-Lara G, Linares-Gonzalez L, Rodenas-Herranz T, et al. Chilblain-like lesions in pediatrics dermatological outpatients during the COVID-19 outbreak[J]. Dermatol Ther,2020,33(5):e13516.
[11]
Riphagen S, Gomez X, Gonzalez-Martinez C, et al. Hyperinflammatory shock in children during COVID-19 pandemic[J]. Lancet,2020, 395(10237):1607-1608.
[12]
World Health Organization. Multisystem inflammatory syndrome in children and adolescents with covid-19[EB/OL].

URL    
[13]
Centers for Disease Control and Prevention. Emergency preparedness and response: mulisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19)[EB/OL].

URL    
[14]
Feldstein LR, Rose EB, Horwitz SM, et al. Multisystem inflammatory syndrome in U.S. children and adolescents[J]. N Engl J Med,2020, 383(4):334-346.
[15]
Pouletty M, Borocco C, Ouldali N, et al. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort[J]. Ann Rheum Dis,2020,79(8):999-1006.
[16]
Galvan Casas C, Catala A, Carretero Hernandez G, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases[J]. Br J Dermatol,2020,183(1):71-77.
[17]
Morey-Olive M, Espiau M, Mercadal-Hally M, et al. Cutaneous manifestations in the current pandemic of coronavirus infection disease (COVID 2019)[J]. An Pediatr (Engl Ed),2020,92(6):374-375.
[18]
Daneshgaran G, Dubin DP, Gould DJ. Cutaneous Manifestations of COVID-19: An Evidence-Based Review[J]. Am J Clin Dermatol,2020,21(5):627-639.
[19]
Torrelo A, Andina D, Santonja C, et al. Erythema multiforme-like lesions in children and COVID-19[J]. Pediatr Dermatol,2020,37(3): 442-446.
[20]
Olisova OY, Anpilogova EM, Shnakhova LM. Cutaneous manifestations in COVID-19: A skin rash in a child[J]. Dermatol Ther,2020,33(6):e13712.
[21]
Klimach A, Evans J, Stevens J, et al. Rash as a presenting complaint in a child with COVID-19[J]. Pediatr Dermatol,2020,37(5):966-967.
[22]
Jia JL, Kamceva M, Rao SA, et al. Cutaneous manifestations of COVID-19: A preliminary review[J]. J Am Acad Dermatol,2020,83(2): 687-690.
[23]
Genovese G, Colonna C, Marzano AV. Varicella-like exanthem associated with COVID-19 in an 8-year-old girl: A diagnostic clue?[J].Pediatr Dermatol,2020,37(3):435-436.
[24]
孙芬芬, 贺斌峰, 何勇. 血管紧张素转化酶2在冠状病毒感染所致肺损伤及其他肺部疾病中研究进展[J/CD]. 中华实验和临床感染病杂志(电子版),2021,15(1):7-10.
[25]
Ortiz-Fernandez L, Sawalha AH. Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations[J]. Genes Immun,2020,21(4):269-272.
[26]
Colmenero I, Santonja C, Alonso-Riano M, et al. SARS-CoV-2 endothelial infection causes COVID-19 chilblains: histopathological, immunohistochemical and ultrastructural study of seven paediatriccases[J]. Br J Dermatol,2020,183(4):729-737.
[27]
Fu Y, Cheng Y, Wu Y. Understanding SARS-CoV-2-mediated inflammatory responses: from mechanisms to potential therapeutic tools[J]. Virol Sin,2020,35(3):266-271.
[28]
Schnapp A, Abulhija H, Maly A, et al. Introductory histopathological findings may shed light on COVID-19 paediatrichyperinflammatory shock syndrome[J]. J Eur Acad Dermatol Venereol,2020,34(11):e665-e667.
[29]
Rodriguez-Jimenez P, Chicharro P, De Argila D, et al. Urticaria-like lesions in COVID-19 patients are not really urticaria--a case with clinicopathologicalcorrelation[J]. J Eur Acad Dermatol Venereol,2020,34(9):e459-e460.
[30]
El Hachem M, Diociaiuti A, Concato C, et al. A clinical, histopathological and laboratory study of 19 consecutive Italian paediatric patients with chilblain-like lesions: lights and shadows on the relationship with COVID-19 infection[J]. J Eur Acad Dermatol Venereol,2020,34(11):2620-2629.
[31]
Mahe A, Birckel E, Merklen C, et al. Histology of skin lesions establishes that the vesicular rash associated with COVID-19 is not 'varicella-like’[J]. J Eur Acad Dermatol Venereol,2020,34(10): e559-e561.
[32]
Verdoni L, Mazza A, Gervasoni A, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study[J]. Lancet,2020,395(10239): 1771-1778.
[33]
Capocasale G, Nocini R, Faccioni P, et al. How to deal with coronavirus disease 2019: A comprehensive narrative review about oral involvement of the disease[J]. ClinExp Dent Res,2021,7(1):101-108.
[34]
Diociaiuti A, Giancristoforo S, Terreri S, et al. Are SARS-CoV-2 IgA antibodies in paediatric patients with chilblain-like lesions indicative of COVID-19 asymptomatic or paucisymptomaticinfection[J]. J Eur Acad Dermatol Venereol,2021,35(1):e10-e13.
[35]
Fernandez-Nieto D, Ortega-Quijano D, Jimenez-Cauhe J, et al. Clinical and histological characterization of vesicular COVID-19 rashes: a prospective study in a tertiary care hospital[J]. Clin Exp Dermatol,2020,45(7):872-875.
[36]
Cepeda-Valdes R, Carrion-Alvarez D, Trejo-Castro A, et al. Cutaneous manifestations in COVID-19: familial cluster of urticarial rash[J]. Clin Exp Dermatol,2020,45(7):895-896.
[37]
Proietti I, Mambrin A, Bernardini N, et al. Urticaria in an infant with SARS-CoV-2 positivity[J]. Dermatol Ther,2020,33(6):e14043.
[38]
Burgi Vieira C, Ferreira AT, Botelho Cardoso F, et al. Kawasaki-like syndrome as an emerging complication of SARS-CoV-2 infection in young adults[J]. Eur J Case Rep Intern Med,2020,7(10):001886.
[39]
张炎, 曹玮, 肖盟, 等. 合并肢端缺血表现的危重型新型冠状病毒肺炎七例临床分析[J]. 中华血液学杂志,2020,41(4):302-307.
[1] 农云洁, 黄小桂, 黄裕兰, 农恒荣. 超声在多重肺部感染诊断中的临床应用价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 872-876.
[2] 王濛, 王華麟, 王鉴, 孙锟. 先天性心脏病宫内诊疗现状与展望[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(05): 481-485.
[3] 李小飞, 刘洪莉, 石丘玲, 田静, 李莉, 漆洪波, 罗欣. 自然分娩产妇低强度聚焦超声子宫复旧治疗防治产后出血的前瞻性随机对照研究[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(05): 534-539.
[4] 姜珊, 李湘燕, 田硕涵, 温冰, 何睿, 齐心. 采用优化抗感染治疗模式改善糖尿病足感染预后的临床观察[J/OL]. 中华损伤与修复杂志(电子版), 2024, 19(05): 398-403.
[5] 许月芳, 刘旺, 曾妙甜, 郭宇姝. 多粘菌素B和多粘菌素E治疗外科多重耐药菌感染临床疗效及安全性分析[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 700-703.
[6] 梁孟杰, 朱欢欢, 王行舟, 江航, 艾世超, 孙锋, 宋鹏, 王萌, 刘颂, 夏雪峰, 杜峻峰, 傅双, 陆晓峰, 沈晓菲, 管文贤. 联合免疫治疗的胃癌转化治疗患者预后及术后并发症分析[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 619-623.
[7] 皮尔地瓦斯·麦麦提玉素甫, 李慧灵, 艾克拜尔·艾力, 李赞林, 王志, 克力木·阿不都热依木. 生物补片修补巨大复发性腹壁切口疝临床疗效分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 624-628.
[8] 顾熙, 徐子宇, 周澍, 张吴楼, 张业鹏, 林昊, 刘宗航, 嵇振岭, 郑立锋. 腹股沟疝腹膜前间隙无张力修补术后补片感染10 例报道[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 665-669.
[9] 臧宇, 姚胜, 朱新勇, 戎世捧, 田智超. 低温等离子射频消融治疗腹壁疝术后补片感染的临床效果[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 687-692.
[10] 杨闯, 马雪. 腹壁疝术后感染的危险因素分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 693-696.
[11] 邢嘉翌, 龚佳晟, 祝佳佳, 陆群. 肺癌化疗患者继发肺部感染的病原菌耐药性及炎症因子变化分析[J/OL]. 中华肺部疾病杂志(电子版), 2024, 17(05): 714-718.
[12] 中华医学会器官移植学分会. 肝移植术后缺血性胆道病变诊断与治疗中国实践指南[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(06): 739-748.
[13] 丛黎, 马林, 陈旭, 李文文, 张亮亮, 周华亭. 改良CT严重指数联合炎症指标在重症急性胰腺炎患者胰腺感染预测及预后评估中的研究[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(05): 432-436.
[14] 贾玲玲, 滕飞, 常键, 黄福, 刘剑萍. 心肺康复在各种疾病中应用的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 859-862.
[15] 颜世锐, 熊辉. 感染性心内膜炎合并急性肾损伤患者的危险因素探索及死亡风险预测[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 618-624.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?