以非伤寒沙门菌菌血症首诊的非霍奇金淋巴瘤一例

doi:10.3877/cma.j.issn.1674-1358.2020.02.015

中华实验和临床感染病杂志(电子版) ›› 2020, Vol. 14 ›› Issue (02) : 167 -171. doi: 10.3877/cma.j.issn.1674-1358.2020.02.015

所属专题：经典病例；经典病例；文献；

病例报告

以非伤寒沙门菌菌血症首诊的非霍奇金淋巴瘤一例

佟晔¹, 张昕宇¹, 周志安², 王立东³^,^†(

)

^1. 067000　承德市，承德医学院
^2. 067000　承德市，承德市中心医院中西医结合科
^3. 067000　承德市，承德市中心医院内分泌科

收稿日期:2019-06-24 出版日期:2020-04-15
通信作者: 王立东

A case of non-hodgkin’s lymphoma first diagnosed as non-typhoid Salmonella bacteremia

Ye Tong¹, Xinyu Zhang¹, Zhian Zhou², Lidong Wang³^,^†()

^1. Graduate School of Chengde Medical University, Chengde 067000, China
^2. Department of Combine Traditional Chinese and Western Medicine, Chengde Central Hospital, Chengde 067000, China
^3. Department of Endocrinology, Chengde Central Hospital, Chengde 067000, China

Received:2019-06-24 Published:2020-04-15
Corresponding author: Lidong Wang
About author:
Corresponding author: Wang Lidong, Email: whlfdjs@126.com

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目的

提高医务工作者对全面系统体格检查的重视以及对住院疑诊患者合并较为少见菌血症的认知。

方法

分析1例以非伤寒沙门菌菌血症首诊的非霍奇金淋巴瘤患者的诊疗过程，并结合相关文献进行复习。

结果

1例66岁既往体健的老年男性以非伤寒沙门菌菌血症为首诊，通过不断追踪病因，完善检查，最终诊断为非霍奇金淋巴瘤，予以综合抗感染等对症治疗后，患者体温正常，病原学指标复查均阴性，病情好转后于上级医院进一步化疗，后期规律随访疗效较好。

结论

及时发现并确诊及规范治疗是控制非伤寒沙门菌感染及隐匿的原发病病情及改善预后的关键。

关键词: 非伤寒沙门菌, 非霍奇金淋巴瘤

Objective

To improve the attention to the comprehensive and systematic physical examination and the understanding of the suspected patients complicated with relatively rare bacteremia.

Methods

The diagnosis and treatment of one case of with non-hodgkin lymphoma who was first diagnosed as non-typhoidal Salmonella were analyzed and relevant literatures were reviewed.

Results

Through tracing the cause continually and auxiliary examination, the hidden illness was discovered of a 66-year-old male patient, who was diagnosed as non-hodgkin lymphoma, while first diagnosed as bacteremia of non-typhoidal Salmonella. After comprehensive anti-infection and symptomatic treatment, the patient’s temperature returned to normal. The etiology turned negative. After his condition improved, the patient was advised to superior hospital to further treatment.

Conclusion

Timely detection, diagnosis and standard treatment were the keys to control the infection of non-typhoid Salmonella and improve the prognosis.

Key words: Non-typhoidal Salmonella, Non Hodgkin lymphoma

图1 患者双膝关节MRI

图2 患者胸壁结节组织活检（HE染色）

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A case of non-hodgkin’s lymphoma first diagnosed as non-typhoid Salmonella bacteremia