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中华实验和临床感染病杂志(电子版) ›› 2016, Vol. 10 ›› Issue (05) : 575 -578. doi: 10.3877/cma.j.issn.1674-1358.2016.05.013

临床论著

留置输尿管支架管合并发热性尿路感染男性患者的临床特点与肾脏形态研究
何恒1,(), 虞玉存2, 何咏3   
  1. 1. 450000 郑州市,郑州市第六人民医院泌尿外科
    2. 450000 郑州市,郑州市中医院外科
    3. 450000 郑州市,郑州市中医院内科
  • 收稿日期:2015-02-27 出版日期:2016-10-15
  • 通信作者: 何恒

Clinical features and renal morphological of the male patients with urinary tract infection and ureteral stent

Heng He1,(), Yucun Yu2, Yong He3   

  1. 1. Urinary Surgery Department, The Sixth People Hospital of Zhengzhou, Zhengzhou 450000, China
    2. Department of Surgical, Zhengzhou Hospital of Traditional Chinese Medicine, Zhengzhou 450000, China
    3. Department of Internal Medicine, Zhengzhou Hospital of Traditional Chinese Medicine, Zhengzhou 450000, China
  • Received:2015-02-27 Published:2016-10-15
  • Corresponding author: Heng He
引用本文:

何恒, 虞玉存, 何咏. 留置输尿管支架管合并发热性尿路感染男性患者的临床特点与肾脏形态研究[J/OL]. 中华实验和临床感染病杂志(电子版), 2016, 10(05): 575-578.

Heng He, Yucun Yu, Yong He. Clinical features and renal morphological of the male patients with urinary tract infection and ureteral stent[J/OL]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2016, 10(05): 575-578.

目的

探讨留置输尿管支架管合并发热性尿路感染男性患者的临床特点与肾脏形态变化。

方法

选取郑州市第六人民医院泌尿外科2012年4月至2015年4月采用留置输尿管支架管治疗且合并热性尿路感染的50例男性患者(观察组)以及同期采用留置导尿管合并尿路感染的50例男性患者(对照组)作为研究对象,对两组患者的血尿常规、病原菌分布及肾脏形态特点并进行比较。

结果

与对照组相比,观察组患者血白细胞计数显著增高,且肾脏炎症病变患者人数显著增加;观察组50例尿细菌培养阳性患者共检出病原菌61株,其中革兰阴性菌47株,革兰阳性菌14株;对照组48例尿细菌培养阳性患者共检出病原菌72株,其中革兰阴性菌41株,革兰阳性菌31株。观察组革兰阴性菌比例显著高于对照组(χ2 = 5.358、P = 0.012)。两组患者术前均未发现肾脏炎症病变;术后观察组50例患者均表现为肾脏炎症病变,而对照组仅2例患者表现为肾脏炎症病变,观察组患者肾脏炎症病变比例显著高于对照组,差异具有统计学意义(χ2 = 12.625,P = 0.001)。

结论

留置输尿管支架管合并发热性尿路感染男性患者临床多表现为血白细胞显著升高,病原菌感染以革兰阴性菌为主,且多伴有肾实质炎症病变。

Objective

To investigate the clinical characteristics and changes of renal morphology in male patients with indwelling ureteral stent combined with febrile urinary tract infection.

Methods

Total of 50 male cases with urinary tract infection and ureteral stent from April 2012 to April 2015 (the observation group), and 50 male cases with urinary tract infection and indwelling catheter at the same time (the control group) were selected. The routine detection of urine and blood, pathogen distribution and renal morphology characteristics of the two groups were compared and analyzed, respectively.

Results

Compared with the control group, the white blood cell count was significantly higher in patients of the observation group, and the number of patients with renal inflammatory disease was significantly increased. In 50 cases of observation group, 61 strains of bacteria with urine bacterial culture positive were detected, among which, 47 strains were Gram-negative bacteria and 14 strains were Gram-positive bacteria. In 48 cases of the control group, 72 strains bacteria with urine bacterial culture positive were detected, among which, 41 strains were Gram-negative bacteria and 31 strains were Gram-positive bacteria. The proportion of Gram-negative bacteria in the observation group was significantly higher than that in the control group (χ2 = 5.358, P = 0.012). The patients in both groups before renal inflammatory lesions were not positive; the postoperative observation group of 50 cases were with renal inflammatory disease. While only 2 patients in the control group showed renal inflammatory lesions kidney inflammation positive ratio was significantly higher in the observation group than that of the control group (χ2 = 12.625, P = 0.001).

Conclusions

The clinical manifestations of the patients with indwelling ureteral stent combined with febrile urinary tract infection were mainly with high white blood cells, Gram-negative bacteria were the main pathogenic bacteria, and were mostly associated with renal parenchymal inflammation.

表1 两组患者的实验室检查结果
表2 两组患者的病原菌分布
表3 两组患者99Tcm-DMSA肾静态显像检查结果[例(%)]
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