| [1] |
Patel S, Rauf A, Khan H, et al. Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies[J]. Biochem Pharmacol,2017,94:317-325.
|
| [2] |
Gheblawi M, Wang K, Viveiros A, et al. Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system[J]. Circ Res,2020,126(10):1457-1475.
|
| [3] |
Li Y, Zhou W, Yang L, et al. Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor[J]. Pharmacol Res,2020,157:104833.
|
| [4] |
Zhou P, Yang XL, Wang XG, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin[J]. Nature,2020,579(7798):270-273.
|
| [5] |
Wan Y, Shang J, Graham R, et al. Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS[J]. J Virol,2020,94(7):e00127-20.
|
| [6] |
Michael L, Andrea M, Vincent M. Functional assessment of cell entry and receptor usage ofr SARS-CoV-2 and other lineage B betacoronaviruses[J]. Nat Microbiol,2020,5(4):562-569.
|
| [7] |
He X, Zhang L, Ran Q, et al. Integrative bioinformatics analysis provides insight into the molecular mechanisms of 2019-nCoV[J]. Med Rxiv,2020. [Online ahead of print].
|
| [8] |
Wrapp D, Wang N, Corbett KS, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation[J]. Science, 2020,367(6483):1260-1263.
|
| [9] |
Somineni HK, Boivin GP, Elased KM. Daily exercise training protects against albuminuria and angiotensin converting enzyme 2 shedding in db/db diabetic mice[J]. J Endocrinol,2014,221(2):235-251.
|
| [10] |
Markus H, Hannah KW, Simon S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blokced by clinically-proven protease inhibitor[J]. Cell,2020,181(2):271-280.
|
| [11] |
Yumiko Imai, Keiji Kuba, Shuan Rao, et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure[J]. Nature,2005, 436(7047):112-116.
|
| [12] |
Li W, Moore MJ, Vasilieva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus[J]. Nature,2003,426(6965):450-454.
|
| [13] |
Kuba K, Imai Y, Rao S, et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury[J]. Nat Med,2005,11(8):875-879.
|
| [14] |
Wang D, Chai XQ, Magnussen CG, et al. Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation[J]. Pulm Pharmacol Ther,2019,58:101833.
|
| [15] |
Ding Y, Wang H, Shen H, et al. The clinical pathology of severe acute respiratory syndrome (SARS): a report from China[J]. J Pathol,2003,200(3):282-289.
|
| [16] |
Miura TA. Respiratory epithelial cells as master communicators during viral infections [J]. Curr Clin Microbiol Rep,2019,6(1):10-17.
|
| [17] |
Qian Z, Travanty EA, Oko L, et al. Innate immune response of human alveolar type Ⅱ cells infected with severe acute respiratory syndrome-coronavirus[J]. Am J Respir Cell Mol Biol,2013,48(6):742-748.
|
| [18] |
Jia H. Pulmonary angiotensin-converting enzyme 2 (ACE2) and inflammatory lung disease[J]. Shock,2016,46(3):239-248
|
| [19] |
Blanco-Melo D, Nilsson-Payant BE, Liu WC, et al. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19[J]. Cell,2020,181(5):1036-1045.
|
| [20] |
Ye J, Zhang B, Xu J, et al. Molecular pathology in the lungs of severe acute respiratory syndrome patients[J]. Am J Pathol,2007,170(2):538-545.
|
| [21] |
Imai Y, Kuba K, Rao S, et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure[J]. Nature,2005,436(7047):112-116.
|
| [22] |
Treml B, Neu N, Kleinsasser A, et al. Recombinant angiotensin-converting enzyme 2 improves pulmonary blood flow and oxygenation in lipopolysaccharide-induced lung injury in piglets[J]. Crit Care Med,2010,38(2):596-601.
|
| [23] |
Wu H, Li Y, Wang Y, et al. Tanshinone ⅡA attenuates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2/angiotensin-(1-7) axis in rats[J]. Int J Med Sci,2014,11(6):578-586.
|
| [24] |
孟莹，余常辉，蔡绍曦, 等. 血管紧张素1-7对博来霉素诱导大鼠肺纤维化的抑制作用[J]. 中华医学杂志,2013,93(20):1585-1589.
|
| [25] |
Uhal BD, Li X, Xue A, et al. Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis[J]. Am J Physiol Lung Cell Mol Physiol,2011,301(3):L269-274.
|
| [26] |
Shao M, Wen ZB, Yang HH, et al. Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells[J]. Biomed Pharmacother,2019,117:109193.
|
| [27] |
Meng Y, Yu CH, Li W, et al. Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway[J]. Am J Respir Cell Mol Biol,2014,50(4):723-736.
|
| [28] |
Morrell NW, Stenmark KR. The renin-angiotensin system in pulmonary hypertension[J]. Am J Respir Crit Care Med,2013,187(10):1138-1139.
|
| [29] |
Ishikane S, Hosoda H, Nojiri T, et al. Angiotensin Ⅱ promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells[J]. Biochem Pharmacol,2018,154:136-147.
|
| [30] |
Ferreira AJ, Shenoy V, Yamazato Y, et al. Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension[J]. Am J Respir Crit Care Med,2009,179(11):1048-1054.
|
| [31] |
Hampl V, Herget J, Bíbová J, et al. Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia[J]. Physiol Res,2015,64(1):25-38.
|
| [32] |
Gwathmey TM, Alzayadneh EM, Pendergrass KD, et al. Novel roles of nuclear angiotensin receptors and signaling mechanisms[J]. Am J Physiol Regul Integr Comp Physiol,2012,302(5):R518-530.
|
| [33] |
Gwathmey TM, Pendergrass KD, Reid SD, et al. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin Ⅱ within the cell nucleus[J]. Hypertension, 2010,55(1):166-171.
|
| [34] |
Ye R, Liu Z. ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway[J]. Exp Mol Pathol,2019,113:104350.
|