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中华实验和临床感染病杂志(电子版) ›› 2018, Vol. 12 ›› Issue (02) : 120 -122. doi: 10.3877/cma.j.issn.1674-1358.2018.02.004

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综述

肝硬化合并皮肤软组织感染研究进展
李聪1, 陈羽婷1, 杨松1,(), 成军1   
  1. 1. 100015 北京,首都医科大学附属北京地坛医院肝病中心肝病三科
  • 收稿日期:2016-12-27 出版日期:2018-04-15
  • 通信作者: 杨松
  • 基金资助:
    北京市卫生系统高层次卫生技术人才培养计划(No.2015-3-108); 北京市医院管理局临床医学发展专项经费资助(No. ZY201402)

Progress on skin and soft tissue infections in patients with liver cirrhosis

Cong Li1, Yuting Chen1, Song Yang1,(), Jun Cheng1   

  1. 1. Division 3 of Center of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
  • Received:2016-12-27 Published:2018-04-15
  • Corresponding author: Song Yang
  • About author:
    Corresponding author: Yang Song, Email:
引用本文:

李聪, 陈羽婷, 杨松, 成军. 肝硬化合并皮肤软组织感染研究进展[J/OL]. 中华实验和临床感染病杂志(电子版), 2018, 12(02): 120-122.

Cong Li, Yuting Chen, Song Yang, Jun Cheng. Progress on skin and soft tissue infections in patients with liver cirrhosis[J/OL]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2018, 12(02): 120-122.

肝硬化患者因其免疫力低下、下肢水肿等原因是皮肤软组织感染的高危人群,常见的皮肤软组织感染部位为下肢,常见的感染类型为蜂窝织炎。与一般人群不同,肝硬化患者合并皮肤软组织感染的病原体以革兰阴性杆菌为主。血清肌酐值和MELD评分为肝硬化患者合并皮肤软组织感染预后不良的预测因素。我国肝硬化患者合并皮肤软组织的病原学与临床特征尚需进一步明确,旨在为优化此类患者的优化管理提供一定的依据。

Patients with liver cirrhosis are in high risk of skin and soft tissue infections for the compromised immune and edema of lower extremity. Lower extremity is the most common position for skin and soft tissue infection for patients with liver cirrhosis. Cellulitis is the most common type of skin and soft tissue infections for these patients. Gram-negative bacillus are the major pathogens for cirrhosis patients with skin and soft tissue infections, which are different from general population. Serum creatinine level and MELD score are prognosis predictors for these patients. Further studies should be carried out to identify the pathogen, clinical characteristics of skin and soft tissue infections in Chinese patients with liver cirrhosis, in order to provide certain basis for optimizing the management of these patients.

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