| 1 |
Global burden of disease (GBD) for hepatitis C[J]. J Clin Pharmacol,2004,44(1):20-29.
|
| 2 |
陈园生，李黎，崔富强, 等. 中国丙型肝炎血清流行病学研究[J]. 中华流行病学杂志,2011,32(9):888-891.
|
| 3 |
Lohmann V, Korner F, Koch J, et al. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line[J]. Science,1999,285(5424):110-113.
|
| 4 |
Ikeda M, Yi M, Li K, et al. Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells[J]. J Virol,2002,76(6):2997-3006.
|
| 5 |
Gates AT, Sarisky RT, Gu B. Sequence requirements for the development of a chimeric HCV replicon system[J]. Virus Res,2004,100(2):213-222.
|
| 6 |
Qi X, Bae A, Liu S, et al. Development of a replicon-based phenotypic assay for assessing the drug susceptibilities of HCV NS3 protease genes from clinical isolates[J]. Antiviral Res,2009,81(2):166-173.
|
| 7 |
Gieseler RK, Marquitan G, Schlattjan M, et al. Hepatocyte apoptotic bodies encasing nonstructural HCV proteins amplify hepatic stellate cell activation: implications for chronic hepatitis C[J]. J Viral Hepat,2011,18(11):760-767.
|
| 8 |
Yon C, Viswanathan P, Rossignol JF, et al. Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells[J]. Antiviral Res,2011,91(3):233-240.
|
| 9 |
Panigrahi R, Chandra PK, Ferraris P, et al. Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1[J]. J Virol,2015,89(1):626-642.
|
| 10 |
Bartenschlager R. Hepatitis C virus molecular clones: from cDNA to infectious virus particles in cell culture[J]. Curr Opin Microbiol,2006,9(4):416-422.
|
| 11 |
Yanagi M, Purcell RH, Emerson SU, et al. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee[J]. Proc Natl Acad Sci USA,1997,94(16):8738-8743.
|
| 12 |
Blight KJ, McKeating JA, Rice CM. Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication[J]. J Virol,2002,76(24):13001-13014.
|
| 13 |
Peng B, Yu M, Xu S, et al. Development of robust hepatitis C virus genotype 4 subgenomic replicons[J]. Gastroenterology,2013,144(1):59-61. e6.
|
| 14 |
Steinmann E, Pietschmann T. Cell culture systems for hepatitis C virus[J]. Curr Top Microbiol Immunol,2013,369:17-48.
|
| 15 |
Appel N, Herian U, Bartenschlager R. Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A[J]. J Virol,2005,79(2):896-909.
|
| 16 |
Blight KJ, McKeating JA, Marcotrigiano J, et al. Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture[J]. J Virol,2003,77(5):3181-3190.
|
| 17 |
Liu S, Nelson CA, Xiao L, et al. Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase[J]. Antiviral Res,2011,89(1):54-63.
|
| 18 |
Wu Y, Liao Q, Yang R, et al. A novel luciferase and GFP dual reporter virus for rapid and convenient evaluation of hepatitis C virus replication[J]. Virus Res,2011,155(2):406-414.
|
| 19 |
Li YP, Ramirez S, Gottwein JM, et al. Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains[J]. Proc Natl Acad Sci USA,2012,109(18):E1101-E1110.
|
| 20 |
Bartosch B, Dubuisson J, Cosset FL. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes[J]. J Exp Med,2003,197(5):633-642.
|
| 21 |
Hsu M, Zhang J, Flint M, et al. Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles[J]. Proc Natl Acad Sci USA,2003,100(12):7271-7276.
|
| 22 |
Cai Z, Zhang C, Chang KS, et al. Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells[J]. J Virol,2005,79(22):13963-13973.
|
| 23 |
Zeisel MB, Felmlee DJ, Baumert TF. Hepatitis C virus entry[J]. Curr Top Microbiol Immunol,2013,369:87-112.
|
| 24 |
Kato T, Furusaka A, Miyamoto M, et al. Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient[J]. J Med Virol,2001,64(3):334-339.
|
| 25 |
Wakita T, Pietschmann T, Kato T, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome[J]. Nat Med,2005,11(7):791-796.
|
| 26 |
Zhong J, Gastaminza P, Cheng G, et al. Robust hepatitis C virus infection in vitro[J]. Proc Natl Acad Sci USA,2005,102(26):9294-9299.
|
| 27 |
Date T, Kato T, Miyamoto M, et al. Genotype 2a hepatitis C virus subgenomic replicon can replicate in HepG2 and IMY-N9 cells[J]. J Biol Chem,2004,279(21):22371-22376.
|
| 28 |
Kato T, Date T, Miyamoto M, et al. Nonhepatic cell lines HeLa and 293 support efficient replication of the hepatitis C virus genotype 2a subgenomic replicon[J]. J Virol,2005,79(1):592-596.
|
| 29 |
Gorzin AA, Ramsland PA, Tachedjian G, et al. Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle[J]. J Viral Hepat,2012,19(3):189-198.
|
| 30 |
Chan K, Robinson M, Yang H, et al. Development of a robust luciferase reporter 1b/2a hepatitis C virus (HCV) for characterization of early stage HCV life cycle inhibitors[J]. Antiviral Res,2013,98(1):85-92.
|
| 31 |
Jiang J, Luo G. Cell culture-adaptive mutations promote viral protein-protein interactions and morphogenesis of infectious hepatitis C virus[J]. J Virol,2012,86(17):8987-8997.
|
| 32 |
Han Q, Xu C, Wu C, et al. Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus[J]. Virus Res,2009,145(1):63-73.
|
| 33 |
Liu S, Xiao L, Nelson C, et al. A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses[J]. PLoS One,2012,7(9):e44965.
|
| 34 |
Tao W, Xu C, Ding Q, et al. A single point mutation in E2 enhances hepatitis C virus infectivity and alters lipoprotein association of viral particles[J]. Virology,2009,395(1):67-76.
|
| 35 |
Grove J, Nielsen S, Zhong J, et al. Identification of a residue in hepatitis C virus E2 glycoprotein that determines scavenger receptor BI and CD81 receptor dependency and sensitivity to neutralizing antibodies[J]. J Virol,2008,82(24):12020-12029.
|
| 36 |
Kim CS, Keum SJ, Jang SK. Generation of a cell culture-adapted hepatitis C virus with longer half life at physiological temperature[J]. PLoS One,2011,6(8):e22808.
|
| 37 |
Brohm C, Steinmann E, Friesland M, et al. Characterization of determinants important for hepatitis C virus p7 function in morphogenesis by using trans-complementation[J]. J Virol,2009,83(22):11682-11693.
|
| 38 |
Lohmann V, Hoffmann S, Herian U, et al. Viral and cellular determinants of hepatitis C virus RNA replication in cell culture[J]. J Virol,2003,77(5):3007-3019.
|
| 39 |
Huang Y, Staschke K, De Francesco R, et al. Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication[J]. Virology,2007,364(1):1-9.
|
| 40 |
Lim YS, Hwang SB. Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type Ⅲalpha and regulates viral propagation[J]. J Biol Chem,2011,286(13):11290-11298.
|
| 41 |
Kaul A, Woerz I, Meuleman P, et al. Cell culture adaptation of hepatitis C virus and in vivo viability of an adapted variant[J]. J Virol,2007,81(23):13168-13179.
|
| 42 |
Kaul A, Stauffer S, Berger C, et al. Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics[J]. PLoS Pathog,2009,5(8):e1000546.
|
| 43 |
Yamamoto M, Sakamoto N, Nakamura T, et al. Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture[J]. Hepatol Res,2011,41(3):258-269.
|
| 44 |
Shrivastava S, Devhare P, Sujijantarat N, et al. Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway[J]. J Virol,2015,90(3):1387-1396.
|
| 45 |
Haqshenas G, Mackenzie JM, Dong X, et al. Hepatitis C virus p7 protein is localized in the endoplasmic reticulum when it is encoded by a replication-competent genome[J]. J Gen Virol,2007,88(Pt 1):134-142.
|
| 46 |
Clarke D, Griffin S, Beales L, et al. Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro[J]. J Biol Chem,2006,281(48):37057-37068.
|
| 47 |
Chandra PK, Gunduz F, Hazari S, et al. Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis[J]. PLoS One,2014,9(9):e108616.
|
| 48 |
Chandra PK, Bao L, Song K, et al. HCV infection selectively impairs type I but not type Ⅲ IFN signaling[J]. Am J Pathol,2014,184(1):214-229.
|
| 49 |
Liu S, Chen R, Hagedorn CH. Direct visualization of hepatitis C virus-infected Huh7.5 cells with a high titre of infectious chimeric JFH1-EGFP reporter virus in three-dimensional Matrigel cell cultures[J]. J Gen Virol,2014,95(Pt 2):423-433.
|
| 50 |
Meyer K, Kwon YC, Liu S, et al. Interferon-α inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection[J]. Sci Rep,2015,5:9012.
|
| 51 |
Ramirez S, Mikkelsen LS, Gottwein JM, et al. Robust HCV genotype 3a infectious cell culture system permits identification of escape variants with resistance to sofosbuvir[J]. Gastroenterology,2016,151(5):973-985.
|
| 52 |
Liu F, Shimakami T, Murai K, et al. Efficient Suppression of hepatitis C virus replication by combination treatment with miR-122 antagonism and direct-acting antivirals in cell culture systems[J]. Sci Rep,2016,6:30939.
|