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中华实验和临床感染病杂志(电子版) ›› 2016, Vol. 10 ›› Issue (03) : 319 -322. doi: 10.3877/cma.j.issn.1674-1358.2016.03.014

临床论著

上消化道症状与幽门螺杆菌感染及胃癌前疾病的相关性
谢琼1,(), 卢月月1, 易宏锋1()   
  1. 1. 434000 荆州市,湖北省荆州市第一人民医院消化内科
  • 收稿日期:2015-07-27 出版日期:2016-06-15
  • 通信作者: 谢琼, 易宏锋

Correlation of upper gastrointestinal symptoms between Helicobacter pylori infection and gastric precancerous disease

Qiong Xie1(), Yueyue Lu1, Hongfeng Yi1,()   

  1. 1. Department of Gastroenterology, The First People’s Hospital of Jingzhou, Hubei 434000, China
  • Received:2015-07-27 Published:2016-06-15
  • Corresponding author: Qiong Xie, Hongfeng Yi
引用本文:

谢琼, 卢月月, 易宏锋. 上消化道症状与幽门螺杆菌感染及胃癌前疾病的相关性[J]. 中华实验和临床感染病杂志(电子版), 2016, 10(03): 319-322.

Qiong Xie, Yueyue Lu, Hongfeng Yi. Correlation of upper gastrointestinal symptoms between Helicobacter pylori infection and gastric precancerous disease[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2016, 10(03): 319-322.

目的

探讨上消化道症状与幽门螺杆菌(HP)感染及胃黏膜癌前病变的相关性。

方法

选择2013年1月至2014年10月于本院门诊初诊为慢性胃炎的患者,其中上消化道症状阳性组的患者360例,上消化道症状阴性组患者360例,所有患者均通过碳14呼气试验进行HP检测及胃镜下活检,分别比较有无上消化道症状与患者HP阳性检出率的相关性;以及有无上消化道症状与胃镜活检诊断为胃癌前疾病的相关性。

结果

上消化道症状阳性组患者HP检出率高于上消化道症状阴性组(χ2 = 353.892、P = 0.000);上消化道症状阳性组患者慢性胃炎伴不典型增生发病率显著高于上消化道症状阴性组,差异具有统计学意义(χ2 =12.328、P = 0.000)。

结论

上消化道症状与HP感染具有相关性,上消化道症状与慢性胃炎伴不典型增生具有相关性。

Objective

To explore the correlation of gastrointestinal symptoms, Helicobacter pylori (HP) infection and gastric precancerous diseases.

Methods

Patients diagnosed as chronic gastritis were selected from January 2013 to October 2014. Then the patients were divided into upper gastrointestinal symptoms of positive group (360 cases) and negative group (360 cases). All patients were tested by 14C breath test and diagnosised with biopsy in endoscopy. The relationship between the upper gastrointestinal symptoms in patients with HP positive rate and the upper gastrointestinal symptoms with endoscopy biopsy diagnosis of precancerous disease were compared, respectively.

Results

The HP detection rate of upper gastrointestinal symptoms positive group was significantly higher than that of negative group (χ2 = 353.892, P = 0.000). The incidence of chronic gastritis with symptoms of upper gastrointestinal dysplasia positive group was significantly higher than that of negative group (χ2 = 12.328, P = 0.000).

Conclusions

Upper gastrointestinal symptoms was correlated with HP infection, and there were relevantion between upper gastrointestinal symptoms and chronic gastritis.

表2 上消化道症状与胃癌前病变检出率的比较[例(%)]
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