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中华实验和临床感染病杂志(电子版) ›› 2016, Vol. 10 ›› Issue (03) : 257 -260. doi: 10.3877/cma.j.issn.1674-1358.2016.03.001

综述

辅助性T淋巴细胞22及其特征性细胞因子白细胞介素-22的研究进展
张沛枫1, 邹美银1, 汪美华1, 章幼奕1,()   
  1. 1. 226006 南通市,南通大学附属南通第三医院感染病科
  • 收稿日期:2015-06-18 出版日期:2016-06-15
  • 通信作者: 章幼奕
  • 基金资助:
    江苏省南通市社会发展计划项目(No. Hs2014081)

Research progress of Helper T lymphocytes 22 cells and their characteristic cytokine interleukin-22

Peifeng Zhang1, Meiyin Zou1, Meihua Wang1, Youyi Zhang1,()   

  1. 1. Department of Infectious Diseases, Nantong The Third People’s Hospital Affiliated to Nantong University, Nantong 226006, China
  • Received:2015-06-18 Published:2016-06-15
  • Corresponding author: Youyi Zhang
引用本文:

张沛枫, 邹美银, 汪美华, 章幼奕. 辅助性T淋巴细胞22及其特征性细胞因子白细胞介素-22的研究进展[J/OL]. 中华实验和临床感染病杂志(电子版), 2016, 10(03): 257-260.

Peifeng Zhang, Meiyin Zou, Meihua Wang, Youyi Zhang. Research progress of Helper T lymphocytes 22 cells and their characteristic cytokine interleukin-22[J/OL]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2016, 10(03): 257-260.

辅助性T淋巴细胞(Th)22是新近发现的Th细胞谱系,细胞表型为CCR4+、CCR6+和CCR10+,主要通过白细胞介素-22(IL-22)发挥作用,在介导炎症反应、组织修复、创口愈合、感染性疾病、肿瘤、肝脏疾病以及自身免疫性疾病中发挥着重要作用,逐渐成为目前研究的热点;本文就其研究进展进行综述。

Helper T lymphocytes (Th) 22 were the newly discovered Th cell lineage with cell phenotypes such as CCR4+, CCR6+ and CCR10+, which could play important roles in mediating inflammatory responses, tissue repair, wound healing, infectious diseases, tumors, liver diseases and autoimmune diseases through interleukin-22 (IL-22), and had gradually become a research hotspot. This paper reviewed about the research progress of Th22 and IL-22.

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